09 September 2026
: Case report 
Multidisciplinary Collaborative Treatment of Mediastinal Castleman Disease: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Yina Lang
BCDEF 1, Jianchang Yao AG 2*
DOI: 10.12659/AJCR.953364
Am J Case Rep 2026; 27:e953364
Figure 4 The pathological features of the patient’s lesion align with the histological characteristics of Castleman disease (hematoxylin-eosin stain). In the interlayered zone, lymphocytes are arranged in concentric circles resembling the layers of an onion, accompanied by penetration of transparent blood vessels through the atrophic germinal center. (A) Low-power view (hematoxylin-eosin, × 25), (B) High-power view (hematoxylin-eosin, × 200), (C) High-power view (hematoxylin-eosin, × 400), (D) High-power view (hematoxylin-eosin, × 800).