Figure 1 Clinical improvement of bilateral stasis dermatitis following intradermotherapy with HMWNCHA and SA in Case 1. Serial clinical photographs of a 77-year-old male patient with bilateral stasis dermatitis treated with intradermal microinjections of HMWNCHA combined with SA. (A) Baseline presentation showing erythematous-violaceous patches, marked xerosis, and skin fissuring affecting both lower legs. (B) Clinical appearance 1 month after the first treatment session, demonstrating improvement in skin hydration and reduction of erythema. (C) Clinical appearance 1 month after the second treatment session (2 months after treatment initiation), showing further improvement in skin quality and lesion severity. (D) Six-month follow-up after the second treatment session (8 months after treatment initiation), demonstrating sustained clinical remission and restoration of skin integrity. R, right leg; L, left leg; HMWNCHA, high-molecular-weight non-crosslinked hyaluronic acid; SA, succinic acid.