Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 January 2003

Extramedullary relapse of acute myeloid leukemia after the second allogeneic stem cell transplantation, manifested as an intussusception of the intestine

Agata Wrzesień-Kuś, Jacek Treliński, Radzisław Kordek, Jerzy Hołowiecki, Tadeusz Robak

Case Rep Clin Pract Rev 2003; 4(4):308-311 :: ID: 449676

Abstract

Background: Extramedullary relapses (EMR) after allogeneic stem cell transplantation (alloSCT) occur in up to 20% of patients with acute myelogenous leukemia (AML). However, isolated EMR are rare.
Case report: We present the case of the patient with relapse of acute myeloid leukemia (AML) after 2nd
allogeneic stem cell transplantation (alloSCT), first manifested as an intussusception of an intestine. His peripheral blood and bone marrow examinations at this time were normal. The explorative laparotomy had shown massive infiltration of the small intestine and the root of mesentery with segmental occlusion of the colon due to invagination. Histopathological examination of the biopsy of the intestine revealed the leukemic infiltration. The patient died 3
weeks after the operation as a result of infectious complications and the progression of leukemia.
Conclusion: Timely diagnosis and early re-induction treatment may give a chance for prolonging the life
of some patients in these rare cases of AML with relapse limited to bowel. However the prognosis
of AML relapsed after alloSCT also in the case of isolated EMR is poor and its management is extremely difficult because of cumulative toxicity of the previous intensive treatment.

Keywords: acute myeloid leukemia, Intussusception, allogeneic stem cell transplantation

Add Comment 0 Comments

23

In Press

01 Mar 2024 : Case report  USA

Complicated Treatment Course of Severe Asymptomatic Hypertriglyceridemia: A Case Report and Literature Review

Am J Case Rep In Press; DOI: 10.12659/AJCR.943858  

04 Mar 2024 : Case report  Switzerland

Unintentional Plastic Blister Ingestion Leading to Intestinal Perforation: A Report of Two Cases

Am J Case Rep In Press; DOI: 10.12659/AJCR.943514  

04 Mar 2024 : Case report  Belgium

Nivolumab-Induced Cytokine Release Syndrome: A Case Report and Literature Review

Am J Case Rep In Press; DOI: 10.12659/AJCR.941835  

05 Mar 2024 : Case report  USA

Intrapulmonary Shunting and Paradoxical Air Embolism in Liver Transplantation: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.943042  

Most Viewed Current Articles

07 Mar 2024 : Case report  USA

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923