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17 September 2013 : Case report  USA

High fluorodeoxyglucose (18F)PET-uptake lymph nodes in a patient with chordoma: Tumor metastasis or sarcoidosis?

Challenging differential diagnosis, Rare disease

Mohamad Hossain GharaviBDEF, Hope Hueizhi WuDE, Steven A. TomsABCDEG

DOI: 10.12659/AJCR.889329

Am J Case Rep 2013; 14:373-375

Abstract

Background: Fluorodeoxyglucose positron emission tomography (FDG-PET) has been used in imaging and staging of malignancies including sacral chordomas.
Case Report: The author’s report describes the coincident pathological diagnosis of sarcoidosis in a 48-year-old male patient with a recurrent sacral chordoma. Chordoma is a low grade malignancy with frequent systemic metastases in advanced disease. Both metastases and sarcoidosis may be high FDG uptake. Unexpected PET findings need to be biopsied in order to make appropriate clinical decision in the management of chordoma.
Conclusions: Lymph nodes involvement in sarcoidosis and neoplastic disease can have similar FDG-PET manifestations.

Keywords: Notochord, Granuloma, imaging

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923