Background: Intraosseous lipomas happen to be one of rarest benign soft tissue tumors with only a little known about its etiology and pathophysiology. A pubmed search using key word “Intraosseous lipoma”. Came back with 165 results. All the sizes and presentations were reviewed and compared with the case we are presenting. We are reporting a 15x20 cm intraosseous lipoma
Case Report: 32-year-old lady with a large intraosseous lipoma in the proximal thigh. The largest reported in English literature
Conclusions: A intraosseous lesion with this size could still be benign even if its lager than 5 cm. Keeping in mind that with a lesion this size malignancy should always be ruled out.

Keywords: intraosseous lipoma, bone tumor, benign