Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

15 November 2013 : Case report  Lebanon

Congenital infantile fibrosarcoma: Association with bleeding diathesis

Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Rare disease, Adverse events of drug therapy

Mayssaa SalmanBCDEF, Nabil J. KhouryAE, Ibarhim KhalifehAE, Hussein A. AbbasE, Marianne MajdalaniADE, Miguel AbboudE, Samar MuwakkitE, Hassan El SolhADE, Raya SaabACDEF

DOI: 10.12659/AJCR.889489

Am J Case Rep 2013; 14:481-485

Abstract

Background: Congenital infantile fibrosarcoma (CIF) is a soft-tissue tumor occurring during the first 2 years of life, most commonly in the extremities. CIF is frequently initially misdiagnosed as a vascular tumor, but its association with bleeding and coagulopathy has not been well characterized.
Case Reports:  We describe 2 infants with CIF presenting with bleeding and coagulopathy, requiring urgent intervention. Both patients did well; one underwent partial resection followed by chemotherapy, and the other received 2 cycles of chemotherapy followed by gross total resection. We also provide a review of all reported cases of coagulopathy in the setting of CIF in the English literature, uncovering an association that seems to be more prevalent in patients diagnosed in the neonatal period, with associated anemia and thrombocytopenia, and a significant mortality rate.
Conclusions: CIF needs to be considered in the differential diagnosis of vascular congenital tumors, especially when there is evidence of bleeding, anemia, or thrombocytopenia.

Keywords: Congenital infantile fibrosarcoma, bleeding, vascular tumor

Add Comment 0 Comments

891 5

Editorial

01 October 2023 : Editorial  USA

Editorial: The Increasing Relevance of Case Reports in Medical Education and Clinical Practice – and How to Write Them

Dinah V. Parums
Science Editor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/AJCR.942670

Am J Case Rep 2023; 24:e942670

0:00

In Press

03 Oct 2023 : Case report  Japan

Two Cases of Athetoid and Dystonic Cerebral Palsy Associated with Degenerative Cervical Spondylotic Myelopa...

Am J Case Rep In Press; DOI: 10.12659/AJCR.941158  

02 Oct 2023 : Case report  Malaysia

Papillary Thyroid Carcinoma Presenting with Chronic Cough and Hemoptysis in Primary Care: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.941089  

30 Sep 2023 : Case report  USA

A 33-Year-Old Man with a 22-Year History of Nephrotic Syndrome Due to Minimal Change Disease Exacerbated Fo...

Am J Case Rep In Press; DOI: 10.12659/AJCR.941621  

29 Sep 2023 : Case report  Japan

Idiopathic Dilated Cardiomyopathy, Cardiac Failure, and Global Cerebral Atrophy Due to Reduced Cerebral Art...

Am J Case Rep In Press; DOI: 10.12659/AJCR.940892  

Most Viewed Current Articles

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

07 Dec 2021 : Case report  USA

Edwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...

DOI :10.12659/AJCR.934347

Am J Case Rep 2021; 22:e934347

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923