Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

15 November 2013 : Case report  Lebanon

Congenital infantile fibrosarcoma: Association with bleeding diathesis

Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Rare disease, Adverse events of drug therapy

Mayssaa SalmanBCDEF, Nabil J. KhouryAE, Ibarhim KhalifehAE, Hussein A. AbbasE, Marianne MajdalaniADE, Miguel AbboudE, Samar MuwakkitE, Hassan El SolhADE, Raya SaabACDEF

DOI: 10.12659/AJCR.889489

Am J Case Rep 2013; 14:481-485

Abstract

Background: Congenital infantile fibrosarcoma (CIF) is a soft-tissue tumor occurring during the first 2 years of life, most commonly in the extremities. CIF is frequently initially misdiagnosed as a vascular tumor, but its association with bleeding and coagulopathy has not been well characterized.
Case Reports:  We describe 2 infants with CIF presenting with bleeding and coagulopathy, requiring urgent intervention. Both patients did well; one underwent partial resection followed by chemotherapy, and the other received 2 cycles of chemotherapy followed by gross total resection. We also provide a review of all reported cases of coagulopathy in the setting of CIF in the English literature, uncovering an association that seems to be more prevalent in patients diagnosed in the neonatal period, with associated anemia and thrombocytopenia, and a significant mortality rate.
Conclusions: CIF needs to be considered in the differential diagnosis of vascular congenital tumors, especially when there is evidence of bleeding, anemia, or thrombocytopenia.

Keywords: Congenital infantile fibrosarcoma, bleeding, vascular tumor

Add Comment 0 Comments

In Press

Case report  Japan

Hidden Inferior Vena Cava Injury: A Case of Missed Diagnosis after Preoperative CT and Laparotomy

Am J Case Rep In Press; DOI: 10.12659/AJCR.943876  

0:00

Case report  Saudi Arabia

Management of Acute Corneal Hydrops Using Compression Sutures and Intracameral Air Injection

Am J Case Rep In Press; DOI: 10.12659/AJCR.944517  

0:00

Case report  Malaysia

Giant Urinary Bladder in a Woman with Down Syndrome: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.944260  

0:00

Case report  Brazil

Successful Case of Double Valve Replacement Surgery Using Autologous Blood Transfusion: A Patient's Autonom...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943675  

0:00

Most Viewed Current Articles

07 Mar 2024 : Case report  USA 39,552

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

10 Jan 2022 : Case report  Germany 31,343

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

23 Feb 2022 : Case report  USA 18,295

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

19 Jul 2022 : Case report  Saudi Arabia 17,997

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923