01 March 2014
: Case report 
Interstitial granulomatous dermatitis successfully treated with etanercept
Unknown etiology, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Adverse events of drug therapy
Zavier Shawkat AhmedBCDEFG, Sabaa JoadACDG, Manpreet SinghAFG, Sabiha S. BandagiADFDOI: 10.12659/AJCR.890074
Am J Case Rep 2014; 15:94-96
Abstract
BACKGROUND: Interstitial granulomatous disease (IGD) is a rare skin condition that presents with erythematous and violaceous plaques, and may be associated with pruritus and pain. The cause remains unknown, but is often associated with autoimmune disease and drug-related adverse effects. It is diagnosed via biopsy, and the treatment remains unclear.
CASE REPORT: We report a case of biopsy-proven IGD associated with rheumatoid arthritis that was treated successfully with etanercept therapy.
CONCLUSIONS: We emphasize that anti-TNF antibodies may be clinically effective for the treatment of IGD.
Keywords: etanercept, rheumatoid arthritis, Interstitial Granulomatous Dermatitis (IGD)
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