06 December 2014 : Case report
Plasmablastic Lymphoma of the Anal Canal in an HIV-Infected Patient
Unusual clinical course, Challenging differential diagnosis, Educational Purpose (only if useful for a systematic review or synthesis)
Lucia Antunes ChagasBDEFG, Gustavo Bittencourt CamiloBDEFG, Dequitier Carvalho MachadoBDEFG, Débora Ribeiro VidalBD, Celso Estevão de OliveiraDE, Gabriela Cumani ToledoDE, Gabriel Peixoto Castro OriaDE, Monique de França SilvaBD, Romulo Varella de OliveiraBDEFG, Agnaldo José LopesBDEFGDOI: 10.12659/AJCR.892313
Am J Case Rep 2014; 15:543-549
Abstract
BACKGROUND: The advent of antiretroviral therapy increased the life expectancy of human immunodeficiency virus (HIV)-positive patients and, consequently, the morbidity and mortality due to neoplasms. Plasmablastic lymphoma is one such neoplasm that generally presents with involvement of the oral cavity; cases of extra-oral involvement are rare.
CASE REPORT: We report a case of plasmablastic lymphoma in a 46-year-old woman for whom the initial clinical manifestation was a painless perineal tumor accompanied by fecal incontinence.
CONCLUSIONS: The possibility of this neoplasm should be considered in patients with HIV/acquired immune deficiency syndrome (HIV/AIDS) because its early diagnosis is essential so that the start of the treatment is not delayed.
Keywords: Diagnosis, Differential, Biopsy, Anus Neoplasms - diagnosis, HIV, HIV Infections - complications, Lymphoma, AIDS-Related - diagnosis, Magnetic Resonance Imaging, Neoplasms, Plasma Cell - diagnosis
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