30 April 2015
: Case report
Unicentric Castleman’s Disease Presenting as a Pulmonary Mass: A Diagnostic Dilemma
Unknown etiology, Mistake in diagnosis, Unusual setting of medical care, Rare disease
Badi RawashdehAE, Mark MeyerB, Dong YiminC, Colon AnthonyE, Duy NguynF, Mohammad MoslemiB, Simin GolestaniBD, Sobonya RichardEF, Samuel KimAEDOI: 10.12659/AJCR.893380
Am J Case Rep 2015; 16:259-261
Abstract
BACKGROUND: Castleman’s disease, or angiofollicular lymphoid hyperplasia, is a rare disorder and can be easily misdiagnosed as lymphoma, neoplasm, or infection. The diagnosis is challenging due to the nonspecific signs and symptoms as well as the rarity of the disease. We present an unusual case of a young girl presenting with an enlarging pulmonary mass that was believed to be infectious in origin.
CASE REPORT: A 16-year-old Native American female from Arizona initially presented with occasional non-productive cough and chest pain. Imaging revealed a 3-cm left upper lobe lobulated mass. This mass was thought to be due to coccidioidomycosis and was treated with fluconazole. Follow-up imaging demonstrated growth of the mass to 4.8 cm. The patient underwent a left video-assisted thoracoscopic left upper lobectomy and mediastinal lymphadenectomy. Histopathological examination revealed Castleman’s disease.
CONCLUSIONS: Pulmonary masses in young patients can be easily misdiagnosed as infections or cancer. We present the case of a 16-year-old female misdiagnosed as having a fungal infection of the lung, which was later revealed to be Castleman’s disease of the left upper lobe.
Keywords: Diagnosis, Differential, Biopsy, Adolescent, Giant Lymph Node Hyperplasia - diagnosis, Lung Diseases - diagnosis, Lymph Nodes - pathology, Tomography, X-Ray Computed
SARS-CoV-2/COVID-19
31 January 2023 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.937955
18 January 2023 : Case report
Am J Case Rep 2023; 24:e938667
30 December 2022 : Case report
Am J Case Rep 2022; 23:e938571
22 December 2022 : Case report
Am J Case Rep 2022; 23:e938003
In Press
01 Feb 2023 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.938498
31 Jan 2023 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.937955
31 Jan 2023 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.938889
27 Jan 2023 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.938548
Most Viewed Current Articles
13 Jul 2022 : Case report
DOI :10.12659/AJCR.936441
Am J Case Rep 2022; 23:e936441
06 Dec 2021 : Case report
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
23 Feb 2022 : Case report
DOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250
17 Feb 2022 : Case report
DOI :10.12659/AJCR.934399
Am J Case Rep 2022; 23:e934399