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13 August 2015 : Case report  USA

A Case of BK Nephropathy without Detectable Viremia or Viruria

Unusual clinical course, Challenging differential diagnosis, Educational Purpose (only if useful for a systematic review or synthesis)

Mahmoud KamelBCEF, Manish KadianB, Maria Nieva SalazarD, Prince MohanE, Sally SelfB, Titte SrinivasA, Maria Aurora Posadas SalasCD

DOI: 10.12659/AJCR.894314

Am J Case Rep 2015; 16:532-535

Abstract

BACKGROUND: BK nephropathy is an evolving challenge among kidney transplant recipients. Diagnosis of BK nephropathy depends on the presence of BK viral inclusions on renal biopsy. Most cases of BK nephropathy are preceded by BK viremia or viruria.

CASE REPORT: We report a case of BK nephropathy found on protocol renal transplant biopsy without associated BK viremia or viruria.

CONCLUSIONS: BK nephropathy may occur even in the absence of BK viremia or viruria. Protocol biopsy is a useful tool to detect these cases.

Keywords: BK Virus, Kidney Diseases - virology, Polyomavirus Infections - therapy, Tumor Virus Infections - therapy

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923