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11 March 2016 : Case report  USA

A Case of Neuro-Behcet’s Disease Presenting with Central Neurogenic Hyperventilation

Unusual clinical course, Challenging differential diagnosis, Educational Purpose (only if useful for a systematic review or synthesis)

Ayham M. AlkhachroumEF, Saba SaeedE, Jaspreet KaurE, Tanzila ShamsE, Michael A. DeGeorgiaEF

DOI: 10.12659/AJCR.895382

Am J Case Rep 2016; 17:154-159

Abstract

BACKGROUND: Behcet’s disease is a chronic inflammatory disorder usually characterized by the triad of oral ulcers, genital ulcers, and uveitis. Central to the pathogenesis of Behcet’s disease is an autoimmune vasculitis. Neurological involvement, so called “Neuro-Behcet’s disease”, occurs in 10-20% of patients, usually from a meningoencephalitis or venous thrombosis. 

CASE REPORT: We report the case of a 46-year-old patient with Neuro-Behcet’s disease who presented with central neurogenic hyperventilation as a result of brainstem involvement from venulitis.

CONCLUSIONS: To the best of our knowledge, central neurogenic hyperventilation has not previously been described in a patient with Neuro-Behcet’s disease.

Keywords: Behcet Syndrome - diagnosis, Alkalosis, Respiratory - etiology, Brain Diseases - diagnosis, Brain Stem - blood supply, Hyperventilation - etiology, Magnetic Resonance Angiography, Respiratory Distress Syndrome, Adult - etiology

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923