Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

22 February 2016 : Case report  USA

Marjolin’s Ulcer Complicating a Pressure Sore: The Clock is Ticking

Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Kamran KhanCDEF, Anna Lucia GiannoneCDEF, Erfan MehrabiF, Ayda KhanF, Roberto E. GiannoneE

DOI: 10.12659/AJCR.896352

Am J Case Rep 2016; 17:111-114

Abstract

BACKGROUND: Malignant degeneration in any chronic wound is termed a Marjolin’s ulcer (MU). The overall metastatic rate of MU is approximately 27.5%. However, the prognosis of MU specific to pressure sores is poor, with a reported metastatic rate of 61%. This is due to insidious, asymptomatic malignant degeneration, a lack of healthcare provider awareness, and, ultimately, delayed management.

CASE REPORT: An 85-year-old white male was noted by his wound-care nurse to have a rapidly developing growth on his lower back over a period of 4 months. There was history of a non-healing, progressive pressure ulcer of the lower back for the past 10 years. On examination, there was a 4×4 cm pressure ulcer of the lower back, with a superimposed 1.5×2 cm growth in the superior region. There was an absence of palpable regional lymphadenopathy. Punch biopsy revealed squamous cell carcinoma consistent with Marjolin’s ulcer. The ulcer underwent excision with wide margins, and a skin graft was placed. Due to the prompt recognition of an abnormality by the patient’s wound-care nurse, metastasis was not evident on imaging. There are no signs of recurrence at 1-year follow-up.

CONCLUSIONS: Marjolin’s ulcer has a rapid progression from local disease to widespread metastasis. Therefore, it is essential that wound-care providers are aware of the clinical signs and symptoms of malignant degeneration in chronic wounds.

Keywords: Carcinoma, Squamous Cell - surgery, Aged, 80 and over, Lumbosacral Region, Pressure Ulcer - complications, Skin Neoplasms - surgery, Surgical Flaps

0 Comments

SARS-CoV-2/COVID-19

31 January 2023 : Case report  USA

Accelerated Cardiac Allograft Vasculopathy in an Orthotopic Heart Transplant Recipient with Prior COVID-19

Am J Case Rep In Press; DOI: 10.12659/AJCR.937955  

18 January 2023 : Case report  Malaysia

Herpes Zoster Following COVID-19 Vaccine Booster

Am J Case Rep 2023; 24:e938667

22 December 2022 : Case report  Gabon

Severe COVID-19 in 2 Kidney Transplant Patients in Gabon

Am J Case Rep 2022; 23:e938003

In Press

01 Feb 2023 : Case report  USA

Intra-Tendinous Ganglion Cyst of the Peroneus Tertius: A Case Report and Literature Review

Am J Case Rep In Press; DOI: 10.12659/AJCR.938498  

31 Jan 2023 : Case report  USA

Accelerated Cardiac Allograft Vasculopathy in an Orthotopic Heart Transplant Recipient with Prior COVID-19

Am J Case Rep In Press; DOI: 10.12659/AJCR.937955  

31 Jan 2023 : Case report  USA

Life-Threatening Retroperitoneal Hemorrhage Following Cyst Rupture in Autosomal Dominant Polycystic Kidney ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938889  

27 Jan 2023 : Case report  Spain

A 37-Year-Old Man with Familial Hereditary Hemorrhagic Telangiectasia and Pulmonary Arteriovenous Malformat...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938548  

Most Viewed Current Articles

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

17 Feb 2022 : Case report  Oman

Myocarditis, Pulmonary Hemorrhage, and Extensive Myositis with Rhabdomyolysis 12 Days After First Dose of P...

DOI :10.12659/AJCR.934399

Am J Case Rep 2022; 23:e934399

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923