08 August 2016
: Case report
Sepsis Caused by Achromobacter Xylosoxidans in a Child with Cystic Fibrosis and Severe Lung Disease
Challenging differential diagnosis, Diagnostic / therapeutic accidents, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Kim StobbelaarABCDEF, Kim Van HoorenbeeckDE, Monique LequesneE, Jozef De DooyE, Erwin HoE, Erika VliegheE, Margaretha IevenE, Stijn VerhulstABCDEDOI: 10.12659/AJCR.896577
Am J Case Rep 2016; 17:562-566
Abstract
BACKGROUND: Achromobacter xylosoxidans is an aerobic, motile, Gram-negative, opportunistic pathogen that can be responsible for various severe nosocomial and community-acquired infections. It has been found in immunocompromised patients and patients with several other underlying conditions, but the clinical role of this microorganism in cystic fibrosis is unclear.
CASE REPORT: We describe a case of septic shock caused by A. xylosoxidans in a 10-year-old child with cystic fibrosis and severe lung disease.
CONCLUSIONS: As the prevalence of A. xylosoxidans in cystic fibrosis patients is rising and patient-to-patient transmission is highly probable, further studies are warranted to determine its role and to document the appropriate treatment strategy for eradication and long-term treatment of this organism.
Keywords: Achromobacter denitrificans, Child, Cystic Fibrosis - complications, Gram-Negative Bacterial Infections - drug therapy, Respiratory Insufficiency - microbiology, Sepsis - microbiology
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