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15 November 2016 : Case report  Qatar

Recurrent Post Tonsillectomy Secondary Hemorrhage in Patients with Factor XIII Deficiency: A Case Series and Review of Literature

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease

Hassen MohammedABDEF, Zaid Abu Rajab ALtamimiABCDEF, Rashid SheikhABE, Hayam Al TaweelADF, Shanmugam GanesanDEF

DOI: 10.12659/AJCR.900391

Am J Case Rep 2016; 17:850-854

Abstract

BACKGROUND: Post-tonsillectomy hemorrhage (PTH) has been reported in the literature as a serious complication after tonsillectomy that has high morbidity and can be life threatening. In cases of recurrent secondary PTH, one should consider coagulopathies as the hidden pathology. Factor XIII deficiency is very rare, suggested to be present 1 in 2 million people. Patients with undiagnosed factor XIII deficiency with secondary PTH are extremely rare. 

CASE REPORT: We report on the cases of six patients (four adults and two children) who presented with recurrent attacks of secondary PTH.

CONCLUSIONS: Recurrent, severe PTH could be related to undiagnosed hematological disorders.

Keywords: Factor XIII Deficiency, Hemorrhage, Tonsillectomy

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923