04 January 2017
: Case report
Hypokalemic Paralysis Complicated by Concurrent Hyperthyroidism and Hyperaldosteronism: A Case Report
Challenging differential diagnosis, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology
Yu-Hsin Hsiao1E, Yu-Wei Fang12D, Jyh-Gang Leu12D, Ming-Hsein Tsai12A*DOI: 10.12659/AJCR.901793
Am J Case Rep 2017; 18:12-16
Abstract
BACKGROUND: Thyrotoxic periodic paralysis (TPP) is commonly observed in patients with acute paralysis and hyperthyroidism. However, there is a possibility of secondary causes of hypokalemia in such a setting.
CASE REPORT: Herein, we present the case of a 38-year-old woman with untreated hypertension and hyperthyroidism. She presented with muscle weakness, nausea, vomiting, and diarrhea since one week. The initial diagnosis was TPP. However, biochemistry tests showed hypokalemia with metabolic alkalosis and renal potassium wasting. Moreover, a suppressed plasma renin level and a high plasma aldosterone level were noted, which was suggestive of primary aldosteronism. Abdominal computed tomography confirmed this diagnosis.
CONCLUSIONS: Therefore, it is imperative to consider other causes of hypokalemia (apart from TPP) in a patient with hyperthyroidism but with renal potassium wasting and metabolic alkalosis. This can help avoid delay in diagnosis of the underlying disease.
Keywords: Hyperaldosteronism, Hypokalemia, Hypokalemic Periodic Paralysis, Thyrotoxicosis
1012 13
In Press
01 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
01 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
01 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
30 Nov 2023 : Case report
Am J Case Rep In Press; DOI:
Most Viewed Current Articles
06 Dec 2021 : Case report
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
07 Dec 2021 : Case report
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
19 Jul 2022 : Case report
DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
13 Jul 2022 : Case report
DOI :10.12659/AJCR.936441
Am J Case Rep 2022; 23:e936441