Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

04 August 2017 : Case report  Qatar

Spinal Abscess Caused by Salmonella Bacteremia in a Patient with Primary Myelofibrosis

Challenging differential diagnosis, Rare coexistence of disease or pathology

Shehab Fareed1ABDEF*, Abdulqadir J. Nashwan1ABDEF, Sulieman Abu Jarir2DE, Ahmed Husain2DE, Dina Sameh Suliman3DE, Friyal Ibrahim3DE, Abbas Moustafa4DE, Muhammad S. Akhter5DE, Mohamed A. Yassin1DE

DOI: 10.12659/AJCR.903482

Am J Case Rep 2017; 18:859-864

Abstract

BACKGROUND: In Primary Myelofibrosis (PMF; a clonal disorder arising from the neoplastic transformation of early hematopoietic stem cells) patients, spinal cord compression (SCC) is a common complication or even a presentation symptom due to extramedullary hematopoiesis (EMH). However, a case of SCC caused by a spinal abscess is unusual. To the best of our knowledge, this is the first case report of this rare condition.

CASE REPORT: We are reporting the case of a 50-year-old male with primary myelofibrosis and long-standing splenomegaly with back pain as a presenting symptom who was found to have spinal cord compression. An MRI was performed, as EMH was suspected. The blood cultures revealed an infection with Salmonella, so the patient was placed on ceftriaxone, with no response. The patient demonstrated substantial clinical improvement after 2 weeks of neurosurgical intervention and pain management.

CONCLUSIONS: In PMF patients, back pain with fever or mild neurological symptoms needs to be investigated urgently because of the high risk of irreversible spinal cord damage leading to partial or complete loss of functional independence and shortened survival. The compression could be related to EMH or infections due to an immunodeficiency.

Keywords: Epidural Abscess, primary myelofibrosis, Salmonella Infections, Spinal Cord Compression

Add Comment 0 Comments

In Press

Case report  Ecuador

Middle-Lobe Bronchus Transection in Blunt Thoracic Trauma From a High-Speed Motor Vehicle Collision: A Case...

Am J Case Rep In Press; DOI: 10.12659/AJCR.946488  

0:00

Case report  Saudi Arabia

Innovative Callus Release Technique for Closed Reduction in Old Fractures: Case Studies and Methodology

Am J Case Rep In Press; DOI: 10.12659/AJCR.946876  

0:00

Case report  Malaysia

Asymptomatic Postpartum Bradycardia: A Case of Spontaneous Resolution in a 34-Year-Old Woman

Am J Case Rep In Press; DOI: 10.12659/AJCR.946560  

0:00

Case report  China

Telitacicept and Tacrolimus Synergy in Managing Refractory Primary Membranous Nephropathy: Case Insights

Am J Case Rep In Press; DOI: 10.12659/AJCR.946727  

0:00

Most Viewed Current Articles

21 Jun 2024 : Case report  China (mainland) 96,182

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

DOI :10.12659/AJCR.944371

Am J Case Rep 2024; 25:e944371

0:00

07 Mar 2024 : Case report  USA 52,159

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

20 Nov 2023 : Case report  Saudi Arabia 31,026

Azithromycin Treatment for Acne Vulgaris: A Case Report on the Risk of Clostridioides difficile Infection

DOI :10.12659/AJCR.941424

Am J Case Rep 2023; 24:e941424

0:00

18 Feb 2024 : Case report  Japan 23,365

A Case of Thoracic Empyema Caused by Actinomyces naeslundii

DOI :10.12659/AJCR.943030

Am J Case Rep 2024; 25:e943030

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923