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26 July 2017 : Case report  Greece

Kaposi Sarcoma in an Human Immunodeficiency Virus (HIV)-Seronegative Mediterranean Female: Report of a Rare Case

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease

Marios Grigoriou1A, Konstantinia E. Kofina1EF*, Aristeidis Ioannidis1B, Domniki K. Gerasimidou2C, Christoforos Efthymiadis1D, Thomas Zaramboukas3D

DOI: 10.12659/AJCR.903537

Am J Case Rep 2017; 18:830-833

Abstract

BACKGROUND: Kaposi sarcoma is a malignancy commonly linked to HIV infection or immunosuppression. An association with human herpes virus 8 (HHV-8) infection has also been reported. We present a case of classic Kaposi sarcoma in a female Mediterranean patient.

CASE REPORT: A 57-year-old white female of Greek ethnicity, with no history of HIV infection or immunosuppression, presented to the Surgical Out-patient Department of our Center, with complaints of extensive discolored skin lesion on both legs, initially considered as chronic vein insufficiency. Histopathological findings from skin biopsies revealed Kaposi sarcoma.

CONCLUSIONS: Non-HIV-related Kaposi sarcoma is an HHV-8-related, angioproliferating skin cancer that can cause pain, disfigurement, and limb dysfunction. High suspicion of this condition can lead to early treatment and delay progression.

Keywords: Immunosuppression, Sarcoma, Kaposi, Skin Abnormalities

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923