18 December 2017 : Case report
Atypical Presentation of Radiation-Associated Breast Angiosarcoma: A Case Report and Review of Literature
Unusual clinical course, Unusual or unexpected effect of treatmentYvette Farran1BEF, Osvaldo Padilla2AB, Karinn Chambers3AD, Alexander Philipovskiy4F*, Zeina Nahleh5ADG
Am J Case Rep 2017; 18:1347-1350
BACKGROUND: Radiation-associated breast angiosarcoma is a rare clinical entity that is thought to be increasing in incidence.
CASE REPORT: Here we present the case of a 67-year-old female with a history of left breast invasive ductal carcinoma who received breast conserving surgery and radiation therapy eight years ago. She then presented with a painless mild skin discoloration of the left breast that had been present for over one year. Mammograms and ultrasounds were normal. A punch biopsy and a subsequent excisional biopsy revealed the diagnosis of angiosarcoma. The patient was treated with mastectomy and had no subsequent recurrences.
CONCLUSIONS: The long-term clinical surveillance for all patients who receive breast conservation surgery is recommended and a high degree of suspicion should be exercised in view of potential atypical presentations of this disease.
Keywords: Heavy Ion Radiotherapy, Hemangiosarcoma, Mastectomy
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