Asymptomatic Meningitis and Lung Cavity in a Case of Cryptococcosis

Aixin Li; Qunhui Li; Caiping Guo; Yulin Zhang

doi:10.12659/AJCR.905905

26 October 2017 : Case report China (mainland)

Asymptomatic Meningitis and Lung Cavity in a Case of Cryptococcosis

Challenging differential diagnosis, Rare coexistence of disease or pathology

Aixin Li^1B, Qunhui Li^1A, Caiping Guo^1F, Yulin Zhang^1DE*

DOI: 10.12659/AJCR.905905

Am J Case Rep 2017; 18:1140-1144

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Abstract

BACKGROUND: Cryptococcus neoformans (C. neoformans) infection is one of the most common opportunistic infections in AIDS patients. C. neoformans usually infects the central nervous system (CNS) and/or lungs with typical clinical manifestation.

CASE REPORT: Here, we report the case of a 52-year-old HIV-1-infected man with disseminated cryptococcosis, including subacute meningitis, pulmonary, and cutaneous cryptococcosis, but only skin lesion served as the chief complaint. Moreover, the results of cerebrospinal fluid (CSF) tests and lung computed tomography (CT) scan were atypical.

CONCLUSIONS: We present the clinical characteristics of this case and discuss the diagnostic procedure, which will likely help clinicians in making a timely definitive diagnosis of this disease.

Keywords: case reports, Cryptococcosis, Cryptococcus neoformans

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