24 April 2018
: Case report 
Tonsillar Small Cell Carcinoma: Potential Contribution of Human Papillomavirus
Unknown etiology
Roger A. Fecher1ADEF, Brittany A. Leader2EF, Yash Patil2AE, Randall Butler3ADE*DOI: 10.12659/AJCR.908252
Am J Case Rep 2018; 19:482-485
Abstract
BACKGROUND: Extrapulmonary small cell carcinoma (SmCC) is a relatively rare clinical entity constituting only 2.5–5% of SmCCs. Recently, evidence has emerged that high-risk types of human papillomavirus (HPV) might play an etiologic role in oropharyngeal SmCC, similar to squamous cell carcinoma.
CASE REPORT: Here, we present a case of tonsillar SmCC that presented as combined SmCC-squamous cell carcinoma in a cervical lymph node, raising the possibility that the SmCC-component represents disease progression.
CONCLUSIONS: This case lends further support to the importance of HPV in the development of oropharyngeal SmCC and suggests a mechanism of disease progression.
Keywords: Carcinoma, Small Cell, Papillomavirus Infections
In Press
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.946838
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.945640
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.945673
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.946476
Most Viewed Current Articles
21 Jun 2024 : Case report
82,085
DOI :10.12659/AJCR.944371
Am J Case Rep 2024; 25:e944371
07 Mar 2024 : Case report
48,695
DOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
20 Nov 2023 : Case report
22,815
DOI :10.12659/AJCR.941424
Am J Case Rep 2023; 24:e941424
07 Jul 2023 : Case report
19,633
DOI :10.12659/AJCR.940200
Am J Case Rep 2023; 24:e940200