Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

10 July 2018 : Case report  Saudi Arabia

An Enlarged Goiter Presenting with a Rare Diffuse Lipomatosis of the Thyroid Gland

Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Dina M. Hijazi1ABCDEF, Firas A. Addas1BF, Najla M. Alghanmi2AB, Hani Z. Marzouki3CDE, Mazin A. Merdad3ACDEFG*

DOI: 10.12659/AJCR.908910

Am J Case Rep 2018; 19:808-811

Abstract

BACKGROUND: Diffuse lipomatosis of the thyroid gland is a particularly rare histopathological condition characterized by diffuse fatty infiltration within the thyroid stroma.

CASE REPORT: We report a case of a 53-year-old woman who presented with a 2-year history of massive neck goiter and mild dysphagia. A computed tomography (CT) scan revealed heterogeneous enhancing of an enlarged thyroid gland with left lobe cranial extension and compression of the pharynx, and caudal bilateral retrosternal growth. The patient underwent total thyroidectomy and histopathological examination revealed mature fatty tissue diffusely distributed throughout the thyroid gland. Excision of the gland was somewhat challenging due to the very thin thyroid capsule and recurrent protrusion of fat from the capsule.

CONCLUSIONS: Diffuse thyroid lipomatosis is an extremely rare histopathological condition characterized by diffuse fatty infiltration in thyroid stroma. Despite its rarity, it should be considered in the differential diagnoses of a patient presenting with a goiter.

Keywords: Goiter, Lipomatosis, Thyroid Diseases

Add Comment 0 Comments

In Press

Case report  China

Management of Post-Kyphoplasty Cement Dislodgement in Osteoporotic Vertebral Fracture: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.947316  

Case report  Japan

Successful Conservative Treatment of Tracheobronchial Injury as a Complication After Emergency Tracheal Int...

Am J Case Rep In Press; DOI: 10.12659/AJCR.947693  

Case report  USA

Aggressive Squamous Cell Lung Carcinoma in a Long-Term E-Cigarette User with Intracardiac Complications: A ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.947911  

Case report  Italy

Twenty Years of Continuous Bisphosphonate Use Leading to Atypical Bilateral Femoral Fractures: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.946435  

Most Viewed Current Articles

21 Jun 2024 : Case report  China (mainland) 100,331

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

DOI :10.12659/AJCR.944371

Am J Case Rep 2024; 25:e944371

0:00

07 Mar 2024 : Case report  USA 53,693

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

20 Nov 2023 : Case report  Saudi Arabia 36,172

Azithromycin Treatment for Acne Vulgaris: A Case Report on the Risk of Clostridioides difficile Infection

DOI :10.12659/AJCR.941424

Am J Case Rep 2023; 24:e941424

0:00

07 Jul 2023 : Case report  Saudi Arabia 24,938

A Classical Case of Cesarean Scar Endometriosis in a 35-Year-Old Woman Presenting with Cyclical Abdominal P...

DOI :10.12659/AJCR.940200

Am J Case Rep 2023; 24:e940200

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923