25 August 2018
: Case report
Improved Bowel Function in Patients with Spina Bifida After Bone Marrow-Derived Mononuclear Cell Transplantation: A Report of 2 Cases
Congenital defects / diseases
Nguyen Thanh Liem1ABCDEFG*, Vu Duy Chinh2ABCDEF, Nguyen Thi Thinh3BCDEF, Ngo Duy Minh3ABCDEF, Hoang Minh Duc1BCDEFDOI: 10.12659/AJCR.909801
Am J Case Rep 2018; 19:1010-1018
Abstract
BACKGROUND: Bowel dysfunction is observed in 42.2–71.2% of patients with spina bifida. Traditional treatments yield limited results. The objective of this paper is to report on improvement in bowel function in 2 children with spina bifida following bone marrow-derived mononuclear cells transplantation.
CASE REPORT: Two patients – 14 years old and 11 years old – with bowel dysfunction after myelomeningocele repair underwent 2 BMMNC transplantations without complications. Those patients had normal defecation, assessed through follow-ups of 21 months and 16 months, respectively.
CONCLUSIONS: BMMNC transplantation can improve bowel function, as demonstrated in 2 patients with spina bifida.
Keywords: adult stem cells, Bone Marrow Transplantation, Spina Bifida Occulta
1393 14
In Press
01 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
01 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
01 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
30 Nov 2023 : Case report
Am J Case Rep In Press; DOI:
Most Viewed Current Articles
06 Dec 2021 : Case report
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
07 Dec 2021 : Case report
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
19 Jul 2022 : Case report
DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
13 Jul 2022 : Case report
DOI :10.12659/AJCR.936441
Am J Case Rep 2022; 23:e936441