Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

14 January 2019 : Case report  Russian Federation

A Case of Pregnancy Complicated by Primary Hyperparathyroidism Due to a Parathyroid Adenoma

Mistake in diagnosis, Rare coexistence of disease or pathology

Natalia G. Mokrysheva1ADE, Anna K. Eremkina1DEF*, Svetlana S. Mirnaya1BEF, Lyudmila Y. Rozhinskaya2AF, Nikolay S. Kuznetsov3BD, Rosa M. Yesayan4BF, Natalia E. Kan5ACD, Ekaterina N. Dudinskaya6CD

DOI: 10.12659/AJCR.912436

Am J Case Rep 2019; 20:53-59


BACKGROUND: Primary hyperparathyroidism is most common in women during the menopause and its occurrence in pregnant women is rare. However, because neonatal mortality is associated with maternal hyperparathyroidism, early diagnosis is essential. This report describes the case of a late diagnosis of primary hyperparathyroidism in a 28-year-old pregnant woman and describes the effects on the mother and neonate.

CASE REPORT: During her second pregnancy, a 28-year-old woman presented with symptoms of general weakness, bone and joint pain, multiple fractures with bone deformity, muscle weakness, and gait disturbance. Due to the high risk of perinatal pathology, a cesarean section was performed. Several weeks later, she underwent thoracoscopic removal of an ectopic parathyroid gland located at the aortic arch. Hypocalcemia in the newborn infant required treatment with calcium and magnesium supplements.

CONCLUSIONS: This case demonstrates that primary hyperparathyroidism during pregnancy requires timely diagnosis and treatment to reduce potential maternal and fetal complications. Screening for primary hyperparathyroidism should be undertaken in pregnant women with any symptoms associated with hypercalcemia. Treatment should be individualized and includes conservative management, parathyroidectomy in the second trimester, or parathyroidectomy performed in the early postpartum period.

Keywords: Hypercalcemia, Hyperparathyroidism, Primary, Osteoporosis, Parathyroid Hormone, Pregnancy, Adenoma, Parathyroid Neoplasms, Parathyroidectomy, Pregnancy Complications, Neoplastic

Add Comment 0 Comments

1340 21

In Press

29 Sep 2023 : Case report  Japan

Idiopathic Dilated Cardiomyopathy, Cardiac Failure, and Global Cerebral Atrophy Due to Reduced Cerebral Art...

Am J Case Rep In Press; DOI: 10.12659/AJCR.940892  

28 Sep 2023 : Case report  Japan

Lifetime Follow-Up of a Patient with Metastatic Prostate Cancer Undergoing Multiple Surgical Resections: A ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.941668  

28 Sep 2023 : Case report  Japan

A 51-Year-Old Woman with Advanced Breast Cancer and a 2-Week History of Nausea and Vomiting Due to Neuromye...

Am J Case Rep In Press; DOI: 10.12659/AJCR.941808  

28 Sep 2023 : Case report  Greece

Surgical Treatment of a Neglected Thumb Volar Plate Injury in an 11-Year-Old Girl: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.940411  

Most Viewed Current Articles

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

07 Dec 2021 : Case report  USA

Edwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...

DOI :10.12659/AJCR.934347

Am J Case Rep 2021; 22:e934347

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923