BACKGROUND: Radiofrequency ablation is a minimally invasive treatment for arrhythmias, including frequent ventricular premature. As a complication of radiofrequency ablation, pseudoaneurysm can be treated conservatively or by ultrasound-guided thrombin injection.

CASE REPORT: We report a case that a possible allergic reaction to thrombin injected into pseudoaneurysm after radiofrequency ablation.

CONCLUSIONS: We hope that the report of successful management of the allergic reaction in this case may be of help to other doctors; we also emphasize the importance of checking the patient’s history of allergies to thrombin when considering treating pseudoaneurysm with thrombin injection.

Keywords: Aneurysm, Catheter Ablation, Hypersensitivity, Thrombin, Aged, 80 and over, Alanine Transaminase, Aneurysm, False, Drug Hypersensitivity, Electrocardiography, Femoral Artery, Fever, Fibrin, Fibrin Fibrinogen Degradation Products, Hemoglobins, Hemostatics, Hypotension, Injections, Intra-Arterial, Leukopenia, Nausea, radiofrequency ablation, Thrombocytopenia, Ventricular Premature Complexes