11 August 2019 : Case report
Unusual or unexpected effect of treatmentNéstor Báez-Ferrer1EF, María Manuela Izquierdo-Gómez1E, Carima Beyello-Belkasem1E, Pablo Jorge-Pérez1A, Martín J. García-González1DE, Julio J. Ferrer-Hita1F, Alejandro De la Rosa-Hernández1E, Javier García-Niebla1EF, Juan Lacalzada-Almeida1AEF*
Am J Case Rep 2019; 20:1182-1188
BACKGROUND: Tumor disease has improved survival due to therapeutic advances and early diagnosis. However, anti-neoplastic treatment involves generating harmful side effects in the body, both in the short-term and in the long-term. One of the most important side effects is cardiovascular disease after radiotherapy, which in addition to being influenced by classic cardiovascular risk factors, can be also be influenced by anti-neoplastic therapy, and represents the main cause of death after a second cancer. We present a case that synthesizes the most relevant and determining aspects of radiotherapy-induced heart disease.
CASE REPORT: We present the case of a 48-year-old male with a personal history of mediastinal Hodgkin lymphoma who was treated with local radiotherapy 20 years ago, and who was admitted to hospital due to dyspnea and oppressive chest pain with efforts. He was diagnosed with severe aortic stenosis, and a coronary angiography confirmed the existence of coronary disease. Two years before, he had been admitted to hospital due to syncope and a pacemaker had been implanted. This patient experienced several cardiovascular complications that could be attributed to the radiotherapy treatment received in his past.
CONCLUSIONS: Radiotherapy shows multiple cardiological complications, especially when applied at the thoracic level. This fact is very relevant, and this report can help determine the aspects of radiotherapy-induced heart disease affecting the mortality and morbidity of these patients.
Keywords: Arrhythmias, Cardiac, Breast Neoplasms, Coronary Artery Disease, Heart Valve Diseases, Hodgkin Disease, Radiotherapy Dosage, Aortic Valve Stenosis, Chest Pain, Dyspnea, Heart, Mediastinal Neoplasms, Radiation Injuries
01 Feb 2024 : Case reportConservative versus Surgical Treatment of Pneumatosis Intestinalis: Experience from a Multidisciplinary Center
Am J Case Rep In Press; DOI: 10.12659/AJCR.943166
08 Feb 2024 : Case reportRight Thigh Mass Metastasis from Lung Cancer Mimicking Primary Soft Tissue Sarcoma: A Case Report
Am J Case Rep In Press; DOI: 10.12659/AJCR.942416
05 Feb 2024 : Case reportUnraveling the Uncommon: A Case Report of Giant Cell Myocarditis and Examination of Existing Literature
Am J Case Rep In Press; DOI: 10.12659/AJCR.942381
Most Viewed Current Articles
10 Jan 2022 : Case reportA Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case reportAtlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19
Am J Case Rep 2022; 23:e936128
05 Mar 2022 : Case reportAcute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...
Am J Case Rep 2022; 23:e935336