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06 December 2019 : Case report  Saudi Arabia

Concurrent Adrenal and Extra-Adrenal Ganglioneuromas: A Case Report

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Educational Purpose (only if useful for a systematic review or synthesis)

Maram Hussein AlGhamdi1ABCDEFG*, Abdullah AlAyed1ABG, Nayef A. AlShabyli1ABG, Nour Hussain AlGhamdi1BEFG, Mohannad AlRasheed1ABCDFG

DOI: 10.12659/AJCR.918568

Am J Case Rep 2019; 20:1817-1820

Abstract

BACKGROUND: Ganglioneuroma is a rare benign sympathetic chain neoplasm which rarely arise from the adrenal gland in adults and exceedingly rare for ganglioneuroma to arise from different origins in the same patient. We present a rare case of retroperitoneal ganglioneuroma concurring with an adrenal ganglioneuroma in an adult patient.

CASE REPORT: A 17-year-old healthy male underwent computed tomography (CT) scan after road traffic accident where he was found to have a left adrenal homogeneous hypovascular lesion with another retroperitoneal lesion seen within the right para-colic gutter with similar radiological features. Successful surgical resection was obtained, and histological diagnosis of both lesions was benign ganglioneuroma.

CONCLUSIONS: Adrenal and extra-adrenal ganglioneuroma can, although rare, concur together. Key findings are the similar radiological appearance of the lesions with typical hypovascular progressive pattern of enhancement. Appropriate pre-surgical diagnosis can aid to proper management since ganglioneuroma needs wide surgical resection due to its high chance of recurrence.

Keywords: Adrenal Glands, Ganglioneuroblastoma, Ganglioneuroma, Adolescent, Adrenal Gland Neoplasms, Neoplasms, Multiple Primary, Retroperitoneal Neoplasms, Tomography, X-Ray Computed

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923