Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

10 January 2020 : Case report  Latvia

Diagnostic Challenges and Treatment Options for Cutaneous T Cell Pseudolymphoma: A Case Study with Rituximab Treatment

Mistake in diagnosis, Diagnostic / therapeutic accidents, Rare disease

Dārta Balode12ABEF*, Ludmila Beļajeva2B, Vanessa Ruesseler3BE, Alexander Quaas3B, Sandra Lejniece12ABDE

DOI: 10.12659/AJCR.919616

Am J Case Rep 2020; 21:e919616

Abstract

BACKGROUND: Pseudolymphoma is a rare disorder that can mimic lymphoma both clinically and histologically. It usually affects middle-aged females. Since pseudolymphoma is a rare disorder not only is diagnosing the condition difficult, but there is also a lack of standardized treatment guidelines. In the literature, anti-CD20 monoclonal antibody rituximab is described as an effective treatment option.

CASE REPORT: 46-year-old female fell ill suddenly with swelling and enlargement of her chin. Multiple skin biopsies were done, which were re-evaluated multiple times as well. Each ended with a new diagnosis for the patient. Finally, in the last revision of biopsy material, pseudolymphoma was confirmed. The patient received multiple courses of corticosteroid treatments – locally and systemically – without long lasting effect. After diagnosis of pseudolymphoma, the patient was started on intravenous rituximab and this treatment was effective.

CONCLUSIONS: Cutaneous pseudolymphoma is a diagnostic challenge. Rituximab is a treatment option for refractory pseudolymphoma. Since there are no treatment guidelines for pseudolymphoma, more clinical studies are needed to establish best treatment options for these patients. Therefore, each reported clinical case is important.

Keywords: Genes, T-Cell Receptor, Pathology, Pseudolymphoma, Antibodies, Monoclonal, Biopsy, Chin, Diagnosis, Differential, Diagnostic Errors, Lymphoma, T-Cell, Cutaneous, Rare Diseases, rituximab, Skin Diseases

Add Comment 0 Comments

In Press

Case report  Greece

Vancomycin Treatment for Pneumobilia in Clostridioides difficile Infection: A Case Analysis

Am J Case Rep In Press; DOI: 10.12659/AJCR.947628  

Case report  Poland

Thoracic Aortic Dissection (Type B) Managed with Emergency Cesarean Section and Thoracic Endovascular Aorti...

Am J Case Rep In Press; DOI: 10.12659/AJCR.947148  

Case report  China

Novel Approach to Retro-Odontoid Pseudotumor Resection without Atlantoaxial Dislocation

Am J Case Rep In Press; DOI: 10.12659/AJCR.946611  

Case report  USA

Understanding Brugada Pattern in Elderly Patients with COVID-19: A Case Study

Am J Case Rep In Press; DOI: 10.12659/AJCR.948042  

Most Viewed Current Articles

21 Jun 2024 : Case report  China (mainland) 97,828

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

DOI :10.12659/AJCR.944371

Am J Case Rep 2024; 25:e944371

0:00

07 Mar 2024 : Case report  USA 52,727

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

20 Nov 2023 : Case report  Saudi Arabia 32,839

Azithromycin Treatment for Acne Vulgaris: A Case Report on the Risk of Clostridioides difficile Infection

DOI :10.12659/AJCR.941424

Am J Case Rep 2023; 24:e941424

0:00

18 Feb 2024 : Case report  Japan 23,613

A Case of Thoracic Empyema Caused by Actinomyces naeslundii

DOI :10.12659/AJCR.943030

Am J Case Rep 2024; 25:e943030

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923