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05 January 2020 : Case report  Saudi Arabia

Missed Gastric Cancer Metastasis to the Appendix: Case Report and Literature Review

Rare disease

Daeya Alhadid1ABDEF*, Abdullah AlShammari12ABE, Hadeel Almana3BD, Mohammad Aburahmah12AEF

DOI: 10.12659/AJCR.920010

Am J Case Rep 2020; 21:e920010


BACKGROUND: Gastric cancer metastasis to the appendix is a rare condition that might present with symptoms of acute appendicitis or remain asymptomatic and be diagnosed incidentally. This report summaries 6 previously reported cases in addition to the presented case.

CASE REPORT: We report a 54-years-old female patient who presented with gastric cancer metastasis to the appendix that was found incidentally in the second surgery when she underwent bowel resection due to bowel entrapment in internal hernia, a complication of her primary gastric cancer surgical intervention. Six case-reports on gastric cancer metastasis to the appendix were reviewed. The metastasis was symptomatic in 4 cases, and solitary in 3 cases. The diagnosis was delayed in 4 cases as there was no evidence of metastasis at the diagnosis of the primary tumor; appendectomy was performed in all cases. The prognosis of the cases varied considerably.

CONCLUSIONS: We question the real incidence of appendiceal metastasis in gastric cancer, and the benefit-risk ratio of appendectomy in every gastrectomy. Guidelines on management of similar cases is also needed.

Keywords: Abdominal Neoplasms, Appendectomy, Neoplasm Metastasis, Adenocarcinoma, Anastomosis, Roux-en-Y, Antineoplastic Combined Chemotherapy Protocols, Appendiceal Neoplasms, Colectomy, delayed diagnosis, Fluorouracil, Gastrectomy, Incidental Findings, leucovorin, Middle Aged, Missed Diagnosis, Organoplatinum Compounds, Postoperative Complications



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Am J Case Rep In Press; DOI: 10.12659/AJCR.938875  

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923