Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

18 March 2020 : Case report  Croatia

Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient

Unusual setting of medical care, Rare coexistence of disease or pathology

Mirna Krkovic1AEG, Andrea Koosova Gajic1ABE, Janja Tarčuković12BEF, Vlatka Sotosek12A*, Tea Stimac34AD, Sanja Balen56AD, Boban Dangubic1DF, Igor Grubjesic1BF

DOI: 10.12659/AJCR.920685

Am J Case Rep 2020; 21:e920685

Abstract

BACKGROUND: Congenital factor X deficiency is a rare inherited coagulopathy. Pregnancies in women with this disorder are often associated with adverse outcomes, including miscarriage, premature labor, and hemorrhage during pregnancy and in the peripartum period. The literature on this disorder is sparse and shows a limited number of successful pregnancies in women with factor X deficiency.

CASE REPORT: In this report, we present the case of a successful pregnancy and term delivery by elective cesarean section in a 39-year-old primigravida with congenital factor X deficiency. Medical management followed the recommendations of an interdisciplinary team comprising specialists in obstetrics, anesthesia, transfusion medicine, hematology, and neonatology. This high-risk pregnancy was successfully brought to term, and a healthy male neonate was delivered by elective cesarean section at 39 weeks’ gestation. The patient’s factor X deficiency (0.19 kIU/L) was treated using 4 units of solvent-detergent-treated fresh frozen plasma (SD-FFP) 1 h before the cesarean section, leading to hemostatic levels of factor X and an uneventful intraoperative course. Postoperatively, the patient’s factor X levels were controlled daily and corrected using SD-FFP as needed, with no clinically significant blood loss.

CONCLUSIONS: SD-FFP can be used to manage congenital factor X deficiency in the peripartum period and maintain perioperative blood loss within normal limits.

Keywords: Factor X Deficiency, Pregnancy Complications, Hematologic, Pregnancy, High-Risk, Cesarean Section, Hematologic Tests, Infant, Newborn, Pregnancy, Term Birth

Add Comment 0 Comments

In Press

Case report  Latvia

Recurrent Angiomatous Meningioma in a Young Adult: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.947185  

Case report  USA

A Rare Case of Severe Pernicious Anemia with Neuropsychiatric Implications

Am J Case Rep In Press; DOI: 10.12659/AJCR.946911  

Case report  China

Neurological and Cardiac Adverse Events in Cervical Cancer Treatment: A Case of Postoperative Sintilimab-In...

Am J Case Rep In Press; DOI: 10.12659/AJCR.947730  

Case report  Poland

A 4-Week-Old Female Infant with Type 3 von Willebrand Disease Presenting with Nosebleeds and Uncontrolled B...

Am J Case Rep In Press; DOI: 10.12659/AJCR.946625  

Most Viewed Current Articles

21 Jun 2024 : Case report  China (mainland) 98,573

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

DOI :10.12659/AJCR.944371

Am J Case Rep 2024; 25:e944371

0:00

07 Mar 2024 : Case report  USA 52,979

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

20 Nov 2023 : Case report  Saudi Arabia 33,819

Azithromycin Treatment for Acne Vulgaris: A Case Report on the Risk of Clostridioides difficile Infection

DOI :10.12659/AJCR.941424

Am J Case Rep 2023; 24:e941424

0:00

07 Jul 2023 : Case report  Saudi Arabia 23,921

A Classical Case of Cesarean Scar Endometriosis in a 35-Year-Old Woman Presenting with Cyclical Abdominal P...

DOI :10.12659/AJCR.940200

Am J Case Rep 2023; 24:e940200

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923