Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

18 March 2020 : Case report  Croatia

Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient

Unusual setting of medical care, Rare coexistence of disease or pathology

Mirna Krkovic1AEG, Andrea Koosova Gajic1ABE, Janja Tarčuković12BEF, Vlatka Sotosek12A*, Tea Stimac34AD, Sanja Balen56AD, Boban Dangubic1DF, Igor Grubjesic1BF

DOI: 10.12659/AJCR.920685

Am J Case Rep 2020; 21:e920685

Abstract

BACKGROUND: Congenital factor X deficiency is a rare inherited coagulopathy. Pregnancies in women with this disorder are often associated with adverse outcomes, including miscarriage, premature labor, and hemorrhage during pregnancy and in the peripartum period. The literature on this disorder is sparse and shows a limited number of successful pregnancies in women with factor X deficiency.

CASE REPORT: In this report, we present the case of a successful pregnancy and term delivery by elective cesarean section in a 39-year-old primigravida with congenital factor X deficiency. Medical management followed the recommendations of an interdisciplinary team comprising specialists in obstetrics, anesthesia, transfusion medicine, hematology, and neonatology. This high-risk pregnancy was successfully brought to term, and a healthy male neonate was delivered by elective cesarean section at 39 weeks’ gestation. The patient’s factor X deficiency (0.19 kIU/L) was treated using 4 units of solvent-detergent-treated fresh frozen plasma (SD-FFP) 1 h before the cesarean section, leading to hemostatic levels of factor X and an uneventful intraoperative course. Postoperatively, the patient’s factor X levels were controlled daily and corrected using SD-FFP as needed, with no clinically significant blood loss.

CONCLUSIONS: SD-FFP can be used to manage congenital factor X deficiency in the peripartum period and maintain perioperative blood loss within normal limits.

Keywords: Factor X Deficiency, Pregnancy Complications, Hematologic, Pregnancy, High-Risk, Cesarean Section, Hematologic Tests, Infant, Newborn, Pregnancy, Term Birth

0 Comments

SARS-CoV-2/COVID-19

21 March 2023 : Case report  Croatia

Kidney Transplantation from a Deceased Donor with COVID-19 Ad26.COV2-S Vaccine-Induced Thrombotic Thrombocy...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938730  

21 March 2023 : Case report  USA

Classical Presentation of Disseminated Blastomycosis in a 44-Year-Old Healthy Man 3 Months After Diagnosis ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938659  

22 February 2023 : Case report  Taiwan

A 30-Year-Old Woman with an 8-Week History of Anxiety, Depression, Insomnia, and Mild Cognitive Impairment ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938732  

22 February 2023 : Case report  Nigeria

Multidrug-Resistant Kocuria rosea and Methicillin-Resistant Staphylococcus aureus Co-Infection in a Nigeria...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938761  

In Press

23 Mar 2023 : Case report  Malaysia

Case Series of Genetically Confirmed Index Cases of Familial Hypercholesterolemia in Primary Care

Am J Case Rep In Press; DOI: 10.12659/AJCR.939489  

22 Mar 2023 : Case report  Jordan

Laparoscopic Cholecystectomy in a Patient with Situs Inversus Totalis and a Double Superior Vena Cava

Am J Case Rep In Press; DOI: 10.12659/AJCR.938774  

22 Mar 2023 : Case report  USA

Rare Case of Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome with Monoclonal Gammo...

Am J Case Rep In Press; DOI: 10.12659/AJCR.939650  

22 Mar 2023 : Case report  USA

Oral and Intranasal Ketamine Use in Treatment-Resistant Catatonia: A Clinical Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.939530  

Most Viewed Current Articles

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

07 Dec 2021 : Case report  USA

Edwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...

DOI :10.12659/AJCR.934347

Am J Case Rep 2021; 22:e934347

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923