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29 January 2020 : Case report  Portugal

Acute Fatty Liver of Pregnancy: Rare, but Potentially Fatal

Challenging differential diagnosis, Management of emergency care, Rare disease

Andreia de Vasconcelos Gaspar1ABCDEF*, Tânia C. Ascensão1BCDE, Isabel Santos Silva1BCEF

DOI: 10.12659/AJCR.921122

Am J Case Rep 2020; 21:e921122

Abstract

BACKGROUND: Acute fatty liver of pregnancy is an obstetric emergency characterized by liver dysfunction, which can lead to severe maternal and fetal complications.

CASE REPORT: A 34-year-old woman, 37 weeks and 2 days pregnant, reported symptoms of nausea, vomiting, jaundice, and prostration. Laboratory findings revealed liver dysfunction and coagulopathy. A clinical diagnosis of acute fatty liver was made and an emergency cesarean section was performed. The postoperative period was complicated by disseminated intravascular coagulation, acute hepatic and renal insufficiency, and pancreatitis.

CONCLUSIONS: Early recognition of this pathology, the interruption of pregnancy, and intensive therapy led to a favorable outcome.

Keywords: Disseminated Intravascular Coagulation, Fatty Liver, Liver Failure, Acute, Pregnancy, Adult, Cesarean Section, Jaundice, Nausea, Postoperative Complications, Pregnancy Complications, Vomiting

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923