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10 February 2020 : Case report  USA

Epidural Steroid Injection-Induced Pancreatitis: A Case Report

Unusual or unexpected effect of treatment, Unexpected drug reaction, Clinical situation which can not be reproduced for ethical reasons, Rare coexistence of disease or pathology

Kaja Richard1ABDEF, Garrett Waggoner1BCD, Matthew Donnan1BDE, Kwabena Ayesu1ADE, Mario Madruga1ACD, Steve J. Carlan2DEF*

DOI: 10.12659/AJCR.921241

Am J Case Rep 2020; 21:e921241


BACKGROUND: Degenerative disc disease of the lumbar spine can be associated with spinal canal and neuroforaminal stenosis, resulting in severe pain. Conservative approaches to treatment are generally recommended initially, especially in the elderly. Epidural corticosteroid injections can provide significant but temporary pain relief and are a commonly performed procedure in pain management. Pancreatitis caused by corticosteroids is unusual and the prognosis typically is good.

CASE REPORT: A 73-year-old woman presented with severe intractable back pain 1 week after lumbar epidural steroid injection for symptomatic spinal stenosis. Imaging confirmed severe multi-level degenerative disc disease of the lumbar spine resulting in severe canal and bilateral neuroforaminal stenosis. Because of abdominal pain and nausea, an abdominal CT and labs were performed, revealing evidence of pancreatic inflammation.

CONCLUSIONS: Lumbar epidural steroid injection may be a risk factor for developing steroid-induced pancreatitis.

Keywords: Epidural Space, Glucocorticoids, Injections, Epidural, Low Back Pain, Spinal Stenosis

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923