Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

16 March 2020 : Case report  USA

A Case of Linear Cutaneous Lupus Erythematosus in a 55-Year-Old Woman

Challenging differential diagnosis, Rare disease

Katarina Milosavljevic1EF*, Emily Fibeger2BE, Andrew R. Virata3C

DOI: 10.12659/AJCR.921495

Am J Case Rep 2020; 21:e921495

Abstract

BACKGROUND: Linear cutaneous lupus erythematosus (LCLE) is uncommon and occurs mainly in children and young adults. To our knowledge, only ten cases of LCLE in adults have been previously reported. A case is presented of LCLE of the left arm in a 55-year-old woman.

CASE REPORT: A 55-year-old Caucasian woman from the Midwestern United States presented with a three-month history of a pruritic linear eruption on the left arm. She had a previous history of methicillin-resistant Staphylococcus aureus (MRSA) infection of the left forearm. She had previously been treated with topical triamcinolone, hydrocortisone cream, hydroxyzine, and two courses of prednisone. Physical examination showed a unilateral and linear erythematous skin lesion of the left arm that contained papules and followed the embryonal developmental epidermal lines of Blaschko. Histopathology of a 4 mm skin punch biopsy showed an interface dermatitis with keratinocyte necrosis and increased dermal mucin. Immunofluorescence of the skin biopsy, including for antinuclear antigen (ANA), was negative. Prednisone treatment reduced the symptoms of pruritis but did not resolve the rash. However, following topical treatment with betamethasone dipropionate cream for between two and three weeks, and the use of sunblock, the skin lesions resolved.

CONCLUSIONS: This rare case of LCLE in an older adult showed a similar response to treatment as other forms of cutaneous lupus erythematosus, with treatment that included topical steroids and sun protection. Also, this case supports that environmental trigger factors, such as prior infections, might provide insights into the etiology of LCLE.

Keywords: Autoimmune Diseases, Dermatology, Diagnosis, Lupus Erythematosus, Cutaneous, Administration, Topical, Age Factors, Anti-Inflammatory Agents, Betamethasone, Exanthema, Forearm, Midwestern United States, Pruritus, Skin, Sunscreening Agents

Add Comment 0 Comments

In Press

Case report  Latvia

Recurrent Angiomatous Meningioma in a Young Adult: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.947185  

Case report  USA

A Rare Case of Severe Pernicious Anemia with Neuropsychiatric Implications

Am J Case Rep In Press; DOI: 10.12659/AJCR.946911  

Case report  China

Neurological and Cardiac Adverse Events in Cervical Cancer Treatment: A Case of Postoperative Sintilimab-In...

Am J Case Rep In Press; DOI: 10.12659/AJCR.947730  

Case report  Poland

A 4-Week-Old Female Infant with Type 3 von Willebrand Disease Presenting with Nosebleeds and Uncontrolled B...

Am J Case Rep In Press; DOI: 10.12659/AJCR.946625  

Most Viewed Current Articles

21 Jun 2024 : Case report  China (mainland) 98,573

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

DOI :10.12659/AJCR.944371

Am J Case Rep 2024; 25:e944371

0:00

07 Mar 2024 : Case report  USA 52,979

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

20 Nov 2023 : Case report  Saudi Arabia 33,819

Azithromycin Treatment for Acne Vulgaris: A Case Report on the Risk of Clostridioides difficile Infection

DOI :10.12659/AJCR.941424

Am J Case Rep 2023; 24:e941424

0:00

07 Jul 2023 : Case report  Saudi Arabia 23,921

A Classical Case of Cesarean Scar Endometriosis in a 35-Year-Old Woman Presenting with Cyclical Abdominal P...

DOI :10.12659/AJCR.940200

Am J Case Rep 2023; 24:e940200

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923