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23 January 2023 : Case report  Mongolia

[In Press] Primary Hepatic Angioleiomyoma: A Case Report

Challenging differential diagnosis, Unusual setting of medical care, Patient complains / malpractice, Rare disease

Tsengelmaa Jamiyan12ABCDEF, Hajime Kuroda3ABCDEF, Ganchudur Luvsan45E, Tserennadmid Munkhnyam4BE, Akinari Kakumoto3E, Bayarmaa Enkhbat12E

DOI: 10.12659/AJCR.938645

Am J Case Rep In Press; DOI: 10.12659/AJCR.938645  

Available online: 2023-01-23, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule

Abstract

BACKGROUND
Primary hepatic angioleiomyoma is a rare mesenchymal tumor that is characterized by blood vessels and smooth muscle. Herein, we report an extremely rare case of primary hepatic angioleiomyoma and discuss the clinicopathological features.
CASE REPORT
A 60-year-old Mongolian man was diagnosed with a hepatic tumor in the second and third segments of screening in 2012. It had been under control by a physician for 10 years. The patient had discomfort and vague pain in the right side of the abdomen since April 2022. Hepatitis virus markers (hepatitis B and hepatitis C) were negative. Plain computed tomography revealed an 80-mm solitary liver lesion in the left lobe with well-defined margins and heterogeneous enhancement. A left hepatectomy was performed in May 2022. The cut surface of the tumor showed a grayish-white, elastic, hard mass with a diameter of 50×80 mm. Histological findings of the tumor revealed that it was clearly demarcated from the surrounding liver tissues with relatively clear boundaries showing thick, muscle-coated blood vessels with perivascular smooth muscle bundles. Immunohistochemical staining showed that the smooth muscle cells were strongly diffuse and positive for smooth muscle actin.
CONCLUSIONS
Clinically, primary hepatic angioleiomyoma should be distinguished from other types of liver tumors, especially liver cancer. In combination with our long-term observation and other case reports, we recommend general follow-up if the preoperative pathological diagnosis can be confirmed and the patient has no other symptoms.

Keywords: Liver Neoplasms; Pathology; Prognosis

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Am J Case Rep In Press; DOI: 10.12659/AJCR.937955  

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Am J Case Rep In Press; DOI: 10.12659/AJCR.938889  

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923