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30 August 2023 : Case report  Saudi Arabia

[In Press] Rare Oral Hemangioma in Pregnancy: A Case Series Providing Clinical Insight into Patient Care

Challenging differential diagnosis, Unusual setting of medical care, Rare coexistence of disease or pathology

Abdullah Saleh Alsheikh1AEF, Sami Alharethy1A, Dhaifallah Mulafikh1AF, Ahmed Naif Alolaywi2EF, Yara Ibrahim Alhamad3EF, Modi Atig Alamer3EF

DOI: 10.12659/AJCR.939821

Am J Case Rep In Press; DOI: 10.12659/AJCR.939821  

Available online: 2023-08-30, In Press, Corrected Proof

Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule


Hemangiomas are defined as benign soft tissue vascular tumors that are histologically classified as capillary, cavernous, or mixed types. Hemangiomas can also be described based on clinical appearance as superficial, mixed, or deep lesions. Following a thorough search, only 3 case reports of superficial protruding lip mass were found in the literature. Other cases of tongue hemangioma have been reported in infants or young toddlers, and only rarely in adults.
The first case was a 43-year-old pregnant woman, with an unremarkable medical and surgical history, in the second trimester who presented to the Otolaryngology Clinic with a chief concern of a progressively growing lesion, measuring 0.7×0.5 cm, over the lateral right side of the tongue for the last 2 weeks after accidentally biting her tongue during dinner. The second case was a 26-year-old woman with unremarkable medical and surgical history who presented to our Otolaryngology Clinic with a chief concern of a non-painful soft fungating pink-red lip lesion 1.5×1 cm across the right lower lip growing for the last 4 months. This lesion appeared during the third trimester of pregnancy following a lip injury that was described as minor trauma.
Although hemangiomas can occur anywhere on the body, they are most commonly found in the head and neck. These lesions are usually recognized quickly by patients and treating physicians and are thus clinically diagnosed. Most vascular benign lesions regress on their own, but if detected early, they are surgically excised for cosmetic and functional reasons.

Keywords: Hemangioma, Capillary; Hemangioma, Cavernous; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Tongue

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923