12 November 2023
: Case report
[In Press] Cervical Spondylosis as a Potential Cause of Venous Hypertensive Myelopathy: A Case Report
Rare disease
Cai Li1BC, Ying Wang1EF, ShaoHua Fan2B, Yuchen Liu3CD, Ying Chen4C, Jianfeng Wang5E, Xinwei He6ACEGAm J Case Rep In Press; DOI: :: ID: 942149
Available online: 2023-11-12, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Venous hypertensive myelopathy (VHM) is generally closely related to spinal vascular malformations, but a small number of other causes of VHM have been reported.
CASE REPORT
This rare case report describes a 74-year-old man with a C3 to C7 disc herniation, posterior spondylolisthesis (degree I) with spinal stenosis, exhibiting comparatively swift decline in neurological function as well as abnormal expansion of the high-signal intensity region on T2-weighted magnetic resonance imaging (MRI), which progressed to the medulla oblongata. Whether spinal cord degeneration is caused by cervical spondylotic myelopathy remains uncertain. Lumbar puncture was not performed because of spinal stenosis. An acute inflammatory process was also considered and the patient received hormone therapy. However, the effect was not significant, and his symptoms worsened after his hormone levels decreased. Repeat cervical MRI demonstrated interval development of diffuse intramedullary increased T2 signal in the spinal cord, which gradually increased to the pons, with cord swelling and degeneration more apparent. His medical history, negative laboratory results, evoked potential examination results, and poor effects of hormone therapy indicated a low probability of spinal inflammatory disease. Posterior C3-C6 expansive open-door cervical laminoplasty with lateral mass screw insertion and C2 and C7 decompression surgeries were performed. The neurological symptoms and abnormal T2-weighted MRI signals significantly improved after the operation.
CONCLUSIONS
VHM can be caused by spondylotic cord compression, leading to spinal cord injury. Therefore, an accurate diagnosis and timely surgery are essential.
Keywords: Myelitis; Spinal Cord; Spondylosis
In Press
07 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
07 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
07 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
05 Dec 2023 : Case report
Am J Case Rep In Press; DOI:
Most Viewed Current Articles
06 Dec 2021 : Case report
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
07 Dec 2021 : Case report
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
19 Jul 2022 : Case report
DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
13 Jul 2022 : Case report
DOI :10.12659/AJCR.936441
Am J Case Rep 2022; 23:e936441