12 April 2025
: Case report
[In Press] Recurrent Angiomatous Meningioma in a Young Adult: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Viktorija Loginova1ABCDEF, Raimonds Mikijanskis2BCD, Daira Krišāne34BCD, Inese Briede

DOI: 10.12659/AJCR.947185
Am J Case Rep In Press; DOI: 10.12659/AJCR.947185
Available online: 2025-04-12, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Abstract
BACKGROUND
Meningiomas stand as the predominant primary intracranial tumors, encompassing a broad spectrum of histological variations. Within this spectrum, angiomatous meningiomas are notable for their significant vascularity within the tumor structure and rarity, making up only 2.1% of all meningiomas. These tumors typically present with slow-onset symptoms, commonly manifesting as seizures and compression-related effects. This report describes a 27-year-old man presenting with seizures and a diagnosis of angiomatous meningioma with postoperative recurrence, emphasizing the challenges in imaging, diagnosis, and disease management.
CASE REPORT
A 27-year-old man presented with a generalized seizure and unconsciousness. He had a history of exposure to chemicals from road construction and logging and smoked for 7 pack years. Initial CT scan revealed a 2.8-cm irregular tumor on the convex surface of his right frontal lobe. Craniotomy and resection of the lesion revealed angiomatous meningioma (central nervous system [CNS] World Health Organization [WHO] grade I). Six months later, control MRI showed recurrence at the excision site (2.4×2.0×1.4 cm). Re-craniotomy confirmed atypical meningioma (CNS WHO grade 2), and the patient received postoperative radiotherapy (56 Gy).
CONCLUSIONS
This case report highlights the importance of MRI in diagnosing angiomatous meningioma, a rare subtype comprising only 2.1% of all meningiomas. Although the tumor was initially resected successfully, its rapid recurrence as a WHO grade 2 atypical meningioma within 6 months underscores the surgical challenges and high recurrence risk associated with its vascular nature. These findings emphasize the need for careful postoperative monitoring and management.
Keywords: Angiomatosis; Central Nervous System; Magnetic Resonance Imaging; Meningioma; Oncology Service, Hospital
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