10 July 2020>: Articles
Total Pancreatectomy with Splenectomy for Multifocal Intraductal Tubulopapillary Neoplasm (ITPN) of the Pancreas Associated with Invasive Component: Report of a Rare Case
Challenging differential diagnosis, Rare disease
Christoforos Kosmidis A , Nikolaos Varsamis A* , Stefanos Atmatzidis B , Georgios Koimtzis A , Stylianos Mantalovas A , Georgios Anthimidis A , Eleni Georgakoudi A , Christina D. Sevva F , Katerina Zarampouka B , Danai Chourmouzi B , Ariadni Leptopoulou A , Sofia Baka A , Maria Kosmidou DDOI: 10.12659/AJCR.924760
Am J Case Rep 2020; 21:e924760
Table 1. Reported cases of multifocal pancreatic ITPN treated with total pancreatectomy.
No. | Age | Gender | Symptom | Location | Size (cm) | Invasive cancer | Follow-up (months) | Outcome | Case, reference |
---|---|---|---|---|---|---|---|---|---|
1 | 48 | M | Jaundice | HBT | 15 | + | 7 | DD | Yamaguchi et al. 2009, []1 |
2 | 61 | M | Exacerbation of DM | HBT | 11.5 | + | 14 | AF | Shibasaki et al. 2012, []25 |
3 | 69 | F | Excessive thirst | HBT | 12 | + | 24 | AF | Kasugai et al. 2013, []26 |
4 | 78 | M | Abdominal pain | HBT | 1.1 | – | NA | NA | Del Chiaro et al. 2014, []27 |
5 | 42 | M | Abdominal pain | HBT | 3.5 | + | 19 | AF | Kölby et al. 2015, []2 |
6 | 74 | M | Weight loss | HBT | 17.5 | + | 9 | AF | Fujimoto et al. 2017, []6 |
7 | 82 | M | Weight loss | HBT | 8.5 | + | 28 | AHM | Our case 2020 |
ITPN – intraductal tubulopapillary neoplasm; M – male; F – female; DM – diabetes mellitus; H – head of the pancreas; B – body of the pancreas; T – tail of the pancreas; NA – not assigned; DD – death related to the disease; AF – alive, free of disease; AHM – alive with hepatic metastases. |