11 October 2020
: Case report 
Diaphragmatic Lipoma in a Woman with Rheumatoid Arthritis: A Case Report and Literature Review
Challenging differential diagnosis, Rare disease
Khaled Z. Alawneh1ABCDEF, Liqaa A. Raffee2ABCDEF*, Khaldoon M. Alawneh3ABCDEF, Husam Alawneh4BCDEF, Abdelwahab Aleshawi4BCDEFDOI: 10.12659/AJCR.925174
Am J Case Rep 2020; 21:e925174
Table 1. Review of case studies that conducted diaphragmatic lipoma investigations.
| No. | Author | Age | Sex | Location | Tumor size | Clinical features | Treatment modality |
|---|---|---|---|---|---|---|---|
| 1 | Margiotta et al. []11 | 85 | F | Right hemi-diaphragm | 20×15×15 cm | Incidental (at autopsy) | Observation |
| 2 | Margiotta et al. []11 | 45 | M | Left pleural cavity, attached to the diaphragm | 15×10×10 cm (1100 g) | Incidental (at autopsy) | Observation |
| 3 | Naomi et. al. []12 | 69 | F | Left hemi-diaphragm | Incidental | Surgery | |
| 4 | Cheon et al. []13 | 4 | F | Right hemi-diaphragm | 8.5×7×6 cm | Intermittent dry cough | Surgery |
| 5 | Smahi et al. []14 | 54 | F | Left hemi-diaphragm | 6×3.5 cm | Basithoracic pain | Surgery |
| 6 | Sakurai et al. []15 | 50 | M | Base of left hemi-diaphragm | Incidental | Surgery | |
| 7 | Sen et al. []16 | 67 | M | Posterior region of the left hemi-diaphragm | 5×5 cm | Incidental | Surgery |
| 8 | Vougiouklakisa et al. []17 | 39 | F | Right hemi-diaphragm | 25×20×18 cm (2850 g) | Incidental (at autopsy) | Observation |
| 9 | Oyar et al. []18 | 50 | M | Bilateral and symmetric diaphragmatic crus lipomas | Diameter of the right: 14.7 mmDiameter of the left: 14.9 mm | Incidental | Observation |
| 10 | Oyar et al. []19 | 37 | F | Left diaphragmatic crus | Incidental | Observation | |
| 11 | Ferguson and Westcott []20 | 69 | M | Left hemi-diaphragm | Diameter: 8 cm | Incidental (at autopsy) | Observation |
| 12 | Ballon and Spector []21 | 45 | F | Left hemi-diaphragm | 4×3×1.5 cm | Incidental (at autopsy) | Observation |
| 13 | Shimizu et al. []22 | 70 | M | Left hemi-diaphragm | Incidental | Surgery | |
| 14 | Aoyagi et al. []23 | 65 | M | Under left hemi-diaphragm | Incidental | Surgery | |
| 15 | Aydin et al. []24 | 56 | F | Right hemi-diaphragm, posterolateral | 7×5 cm | Chest pain | Surgery |
| 16 | Aydin et al. []24 | 59 | M | Right hemi-diaphragm, posterolateral | 6×5 cm | Chest pain | Surgery |
| 17 | Aydin et al. []24 | 77 | F | Right hemi-diaphragm, posterolateral | 6×4 cm | Chest pain and hemoptysis | Surgery |
| 18 | Aydin et al. []24 | 54 | M | Right hemi-diaphragm, posterolateral | 5×5 cm | Cough, back pain, hemoptysis | Surgery |
| 19 | Aydin et al. []24 | 65 | F | Right hemi-diaphragm, posterolateral | 8×5 cm | Cough, Sputum | Surgery |
| 20 | Papachristos et al. []25 | 66 | F | Left hemi-diaphragm, posterolateral | 16×14.5×5.5 cm | Respiratory failure with progressive dyspnea and left pleuritic chest pain | Surgery |
| 21 | Clagett and Johnson []26 | 45 | F | Left hemi-diaphragm | – | Incidental (at autopsy) | Observation |
| 22 | Clagett and Johnson []26 | 80 | F | Right hemi-diaphragm | Diameter: 1 cm | Incidental (at autopsy) | Observation |
| 23 | Clagett and Johnson []26 | 58 | F | Right hemi-diaphragm | Diameter: 1 cm | Incidental (at autopsy) | Observation |
| 24 | Soderlund []27 | 51 | F | Left Hemi-diaphragm | Diameter: 6 cm | Severe left chest pain | Surgery |
| 25 | Pavlica []28 | 78 | M | Left hemi-diaphragm | Severe chest pain with fatal rupture of diaphragm following a severe episode of vomiting | Resulted in death | |
| 26 | Clark []29 | 65 | F | Right | Incidental | Observation | |
| 27 | Soto []30 | 14 | M | Left | Chest pain | Surgery | |
| 28 | Weilgoni []31 | 57 | M | Right | Incidental | Observation | |
| 29 | Weilgoni []31 | 59 | F | Left | Incidental | Observation | |
| 30 | Weilgoni []31 | 68 | F | Left | Incidental | Observation | |
| 31 | Weilgoni []31 | 64 | F | Left | Incidental | Observation | |
| 32 | Weilgoni []31 | 75 | M | Right | Incidental | Observation | |
| 33 | Weilgoni []31 | 72 | M | Right | Incidental | Observation | |
| 34 | Weilgoni []31 | 69 | M | Left | Incidental | Observation | |
| 35 | Our case | 52 | F | Right | Incidental | Observation | |
| F – Female; M – Male. | |||||||