A Cecal Mucormycosis Mass Mimicking Colon Cancer in a Patient with Renal Transplant: A Case Report and Literature Review

19 October 2020 : Case report Saudi Arabia

Unusual clinical course, Challenging differential diagnosis, Management of emergency care

Saleh Busbait^1ABCDEF*, Zainab AlMusa^2BDF, Mohammed Al Duhileb^3AB, Ayed A. Algarni^4BCD, Ameera Balhareth^3ACDF

DOI: 10.12659/AJCR.926325

Am J Case Rep 2020; 21:e926325

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Table 1. Summary of reports on colonic mucormycosis in recipients of renal transplant in recent medical literature.

Age (years)/Sex	Morbidity	Time since renal Tx	Immuno-suppressor	Sites	Symptoms	Operation	Antifungal medication	Outcome	References	Year
57/M	HTN, DM	2 months	Tacrolimus, MMF, steroids	Stomach, splenic colon, spleen	Abdominal pain, distention, constipation	Debridement of all involved organs	Itraconazole → Amphotericin B	Died on POD 8	18	2001
33/M	---	1 week	Cyclosporine, steroids	Cecum, ascending colon	Hematochezia	Transplant Nephrectomy on day 35	Amphotericin B	Survived	12	2001
43/F	---	8 years (first Tx) 13 weeks (second Tx)	Sirolimus, MMF, steroids	Cecum	Fever, abdominal pain, hematochezia		Amphotericin B for 6 weeks	Survived	19	2005
66/M	---	Not stated	Tacrolimus, MMF	Cecum, terminal ileum	Fever, SOB, abdominal pain	Right hemicolectomy, end ileostomy, mucus fistula	Fluconazole	Died on POD 48	20	2014
64/ M	HTN, MDS	11 years	Tacrolimus	Cecum	Abdominal pain, vomiting, diarrhea	Right hemicolectomy, end ileostomy, mucus fistula	Fluconazole → Amphotericin B	Died on POD 8	---	---
HTN – hypertension; DM – diabetes mellitus; MMF – mycophenolate mofetil; MDS – myelodysplastic syndrome; SOB – shortness of breath; Tx – transplant; POD – postoperative day.

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