Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Induced by Long-Term Use of Citalopram and Short-Term Use of Naproxen

18 September 2020 : Case report USA

Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons, Rare coexistence of disease or pathology

Chia-Yu Chiu^1BCDEF*, Amara Sarwal^1EF, Rehan Azhar Munir^1AF, Michael Widjaja^1CD, Amna Khalid^1BC, Rajan Khanna^1ADF

DOI: 10.12659/AJCR.926561

Am J Case Rep 2020; 21:e926561

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Table 1. Laboratory values and management of the patient.

	4 years ago	10 months ago	Day 1	Day2	Day 3	Day 5	Day 7	Day 10	Day 14	Day 30	Day 90
Sodium (mmol/L)	140	129	113	112	113	118	128	131	133	137	136
Potassium (mmol/L)	4.7	4.5	4.7	4.4	4.2	4.2	4.9	4.7	4.5	4.4	4.6
Chloride (mmol/L)	100	91	76	77	77	82	90	93	97	95	97
BUN (mg/dL)	15	10	7	6	7	10	13	10	17	23	19
Creatinine (mg/dL)	0.8	0.6	0.47	0.47	0.47	0.48	0.52	0.65	0.97	1	1
Uric acid (mg/dL)			1.8			2.8
Serum osmolality (mOsm/kg)			240			271

Intervention		Stop Citalopram and Naproxen							Start Meloxicam 15 mg daily
Fluid intake		limited fluid intake to 1 L per day			limited fluid intake to 0.5 L per day
Sodium tablet					Sodium tablet 2 g twice a day

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