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23 October 2020 : Case report  

Amiodarone Toxicity Presenting with Acute Onset of Systemic Inflammatory Response Syndrome and Multiorgan Failure Mimicking Sepsis

Irfanali R. Kugasia1ABCDEF*, Mohsin Ijaz1CDE, Ahsan Khan1BC, Yashwanth Jasti2FG

DOI: 10.12659/AJCR.926929

Am J Case Rep 2020; 21:e926929

Table 4. Differential diagnoses considered as the possible cause of patient’s clinical symptoms and tests done to rule them out.

Sr. No.Differential diagnosesTests done to rule it out
1.Infectious etiologyNegative results from: Multiple blood cultures Sputum cultures Respiratory multiplex RT-PCR from nasal swab. Broncho-alveolar lavage tested for: bacterial culture and sensitivity, fungal smear and culture, AFB smear and culture, legionella culture, Nocardia cultures, respiratory multiplex RT-PCR. SARS CoV2 PCR nasal swab CT chest, abdomen and pelvis negative for any infectious etiology
2.HyperthyroidismNormal TSH, T3, T4, no exogenous ingestion of thyroid hormone
3.TTP/HUSNormal peripheral smear, haptoglobin level and LDH level
4.LymphomaFlow cytometry from needle aspiration of mediastinal lymph node
5.Piperacillin/Tazobactam Drug feverDiscordant timeframe of symptom onset. Symptoms present prior to starting of the medications, persistent even after its discontinuation
6.OTC Drug interactionNone per history
7.MalignancyNegative on lung biopsy

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923