12 November 2020
: Case report
Possible Azithromycin-Induced Life-Threatening Arrhythmia Requiring Extracorporeal Membrane Oxygenation Support: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Adverse events of drug therapy
Abdulrazaq S. Al-Jazairi1ABCDEF*, Haifa S. Alotaibi1ABCDEFDOI: 10.12659/AJCR.926951
Am J Case Rep 2020; 21:e926951
Table 3. Adverse drug reaction probability scale [11].
Question | Yes | No | Do not know | Score |
---|---|---|---|---|
1. Are there previous conclusive reports on this reaction? | +1 | 0 | 0 | +1 |
2. Did the adverse event appear after the suspected drug was administered? | +2 | −1 | 0 | +2 |
3. Did the adverse event improve when the drug was discontinued or a specific antagonist was administered? | +1 | 0 | 0 | +1 |
4. Did the adverse event reappear when the drug was readministered? | +2 | −1 | 0 | 0 |
5. Are there alternative causes that could on their own have caused the reaction? | −1 | +2 | 0 | −1 |
6. Did the reaction reappear when a placebo was given? | −1 | +1 | 0 | 0 |
7. Was the drug detected in blood or other fluids in concentrations known to be toxic? | +1 | 0 | 0 | 0 |
8. Was the reaction more severe when the dose was increased or less severe when the dose was decreased? | +1 | 0 | 0 | 0 |
9. Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | +1 | 0 | 0 | 0 |
10. Was the adverse event confirmed by any objective evidence? | +1 | 0 | 0 | +1 |
Total score: 4 |