Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

08 April 2021: Articles

A 58-Year-Old Woman with Acute Gastric Perforation Due to Metastatic Ductal Carcinoma 18 Years Following Bilateral Mastectomy for Invasive Ductal Carcinoma of the Breast

Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents, Unusual setting of medical care, Educational Purpose (only if useful for a systematic review or synthesis)

William A. Nehmeh A* , Joseph Derienne A , Léa El Khoury B , Serge Kassar B , Viviane Trak-Smayra B , Roger Noun A , Ghassan Chakhtoura A

DOI: 10.12659/AJCR.927094

Am J Case Rep 2021; 22:e927094

Table 1. Characteristics of gastric metastasis of breast cancer: Cases in the literature since 2005.

AuthorsYearNumber of casesAge [range] (years)Histological typeERPRHER2
Akcali et al []11 2005150IDLNANANA
Kudo et al []12 2005159NANANANA
Whitty et al []13 2005155IDC++NA
Jones et al []14 200725161ILCILC++++−NA
Dumoulin et al []15 2009160ILC++
Pectasides et al []16 200984452636758617549ILCIDC ILC ILCIDC ILCILCILCNA NANANANANA NA NANANANANANANA NANANANA NANANANANANA
Vennapusa et al []17 2010161ILC++NA
Yamamoto et al []18 2010180IDCNA
Almubarak et al []8 20113555 [37−74]34 ILC1 IDC19+2−1+1−19+2−1+1−19−2−1+1+
Koike et al []20 20113425454ILCILCIDC++++++−−−
Abid et al []21 2013159ILC++
Loubna et al []22 201327050IDCIDC−−−−NA+
Hild et al []23 2014153ILC++
Eren et al []24 2014137ILC++NA
Waseda et al []25 2015157ILC++NA
Buka et al []26 2016158ILC++
El Hage et al []27 201654266587570ILCILCILCILCILC++++++−+++−−+−−
Wong et al []28 2016172ILC++
Rodrigues et al []29 201612[40−86]5 ILC7 IDC+11/12+ 6/9+ 2/3
Yim et al []30 2017165ILC+
Barranco et al []31 2017148IDC+NA
Gurzu et al []32 201826873ILCIDC+−−−NA+
Woo et al []33 2018151ILC++
De Gruttola et al []10 2019161ILC++
D2 – D2 lymphadenectomy; ER – estrogen receptor; GM – gastric metastasis; HER2 – human epidermal growth factor receptor; IDC – invasive ductal carcinoma; ILC – invasive lobular carcinoma; MS – mean survival; NA – not available; PR – progesterone receptor; STG – subtotal gastrectomy; TG – total gastrectomy.
AuthorspTNMInterval to GM [range] (months)PerforatedTreatment for gastric metastasisOther metastasisSurvival (months)
Akcali et al []11 T2N0M0108NoTG+ chemotherapyNoAlive at 41
Kudo et al []12 NA48NoEndoscopic resectionNoAlive at 24
Whitty et al []13 T2N0M0131NoTG+ Total colectomyNoNA
Jones et al []14 T2T3N136168NoNoTG + D2ChemotherapyBoneBone, brainPalliative careNA
Dumoulin et al []15 pT1cN1M0120NoDiagnostic laparoscopyPeritoneal carcinosisPalliative care
Pectasides et al []16 NANANANANANANANA351855238508244NoNoNoNoNoNoNoNoChemotherapy for allOvaries, boneBone, lungNoNoSkin, lung, bonePeritoneum, boneBoneNoDead after 11Dead after 23Alive at 9Alive at 44Dead after 4Dead after 9Dead after 1Alive at 39
Vennapusa et al []17 T2N1M10NoChemotherapyRibs, vertebrae, orbitNA
Yamamoto et al []18 pT2N2M06NoChemotherapyBrainAlive at 12
Almubarak et al []8 9T115T28T33T457 [0–230]No4 TG3 Bypass26 Chemotherapy2 Hormonotherapy20: Bone, liver, peritoneum, skin, colorectal, esophagus53% overall 24 months survival
Koike et al []20 NANANANANANANoNoNoChemotherapyChemotherapyChemotherapyNoBoneBoneAlive at 56Dead after 58Dead after 27
Abid et al []21 T1N1M10NoChemotherapyColonNA
Loubna et al []22 T4N2M0pT1cN0M01260NoNoChemotherapySurgeryNoNoDead after 3Alive at 18
Hild et al []23 T3N284NoChemotherapyNoAlive at 30
Eren et al []24 NA72NoChemotherapyNADead after 3
Waseda et al []25 NA60NoChemotherapyLiverNA
Buka et al []26 NA−14NoTG + D2ColorectalDead after 86
El Hage et al []27 T3N2M1T1bN1M1T2N2M0T2NxM1T2N3M106840218NoNoNoNoNoChemotherapy for allNoYesYesYesYesNADead after 11Dead after 13Dead after 1Dead after 19
Wong et al []28 pT2N0M048YesLaparotomy for perforated ulcerNoAlive at 12
Rodrigues et al []29 NA[0–156]No8 chemotherapy4 surgery: 3 TG +D21 STG +D210/12: 9 Bone3 Lungs 1 Large bowel 1 liver 1 skin 2 esophagus 1 mediastinumMS: 14.58MS 4 surgical cases: 38
Yim et al []30 pT2N3M048NoChemotherapyBoneNA
Barranco et al []31 NA0YesNoneNAInstant death
Gurzu et al []32 NANA024YesNoTG + D1STG + D1NANADead after 2Alive at 4
Woo et al []33 pT3N3M112NoSTG with Bilroth II+ D2Bone, ovary, bone marrow, omentumAlive at 66
De Gruttola et al []10 T3N0M096YesTG + HormonotherapyNoAlive at 6
D2 – D2 lymphadenectomy; ER – estrogen receptor; GM – gastric metastasis; HER2 – human epidermal growth factor receptor; IDC – invasive ductal carcinoma; ILC – invasive lobular carcinoma; MS – mean survival; NA – not available; PR – progesterone receptor; STG – subtotal gastrectomy; TG – total gastrectomy.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923