16 December 2020: Articles
A 61-Year-Old Man with SARS-CoV-2 Infection and Venous Thrombosis Presenting with Painful Swelling and Gangrene of the Lower Limb Consistent with Phlegmasia Cerulea Dolens
Rare disease
Abayomi Bamgboje E* , Jungrak Hong E , Savi Mushiyev E , Gerald Pekler EDOI: 10.12659/AJCR.928342
Am J Case Rep 2020; 21:e928342
Table 1. Blood results.
| Markers of coagulopathy | Result |
|---|---|
| D-Dimer | 3,612 ng/dL (0–230 ng/dl) high |
| Cardiolipin antibodies | Positive |
| Cardiolipin immunoglobulin (Ig)G | 60.5 GPL (0.0–12.5) GPL high |
| Cardiolipin IgM | 44.5 MPL (0.0–12.5 MPL) high |
| Cardiolipin IgA | 8.8 APL (0.0–12.5 APL) normal |
| Beta-2 glycoprotein | Positive |
| Beta-2 glycoprotein IgM | 61.9 SMU (≤20.0 SMU) high |
| Beta-2 glycoprotein IgG and IgA | 5 SGU and 5.9 SAU respectively (normal) |
| Homocysteine | 6.8 μmol/l (≤15.0 μmol/L) normal |
| Factor V Leiden mutation | Negative |
| Prothrombin mutation analysis | Negative for prothrombin G20210A mutation |
| International normalized ratio | 1.1 |
| Activated partial thromboplastin time | 31.6 (25.1–36.5) normal |
| Fibrinogen | 283 (200–393 mg/dL) normal |
| Markers of infection/inflammation | Result |
| Procalcitonin | 0.28 ng/mL (0.02–0.08 ng/mL) high |
| C-reactive protein | 6.11 mg/dL (0.00–0.40 mg/dL) high |
| Ferritin | 444 ng/mL (30–400 ng/mL) high |
| Blood culture | Negative |
| Blood biochemistry | Result |
| Creatinine | 1.4 mg/dL (0.7–1.2mg/dl) high |
| Blood urea nitrogen | 35 mg/dL (6.0–20.0 mg/dl) high |
| Lactic acid | 3.1 mmol/L (0.5–2.0 mmol/L) high |
| Probrain natriuretic peptide | 1,716 pg/mL (1.0–125.0 pg/mL) high |
| Arterial blood gas | pH 7.30 low |
| Lactase dehydrogenase | 758 U/L (135–225 U/L) high |
| Albumin | 3.5 mg/dL (3.5–5.2 mg/dL) normal |
| Total protein | 8.0 g/dL (6.6–8.7 g/dL) normal |
| Alkaline phosphatase | 352 U/L (40–129 U/L) high |
| Aspartate transaminase | 74 U/L (0–40 U/L) high |
| Alanine transaminase | 61 U/L (0–41 U/L) high |
| Total bilirubin | 1.3 mg/dL (0.0–1.2 mg/dL) high |
| Blood count | Result |
| White blood cell count | 19,530 cell/mm (4.30–11.00 cell/mm) |
| Hemoglobin | 11.1 g/dL (14.0–18.0 g/dL) |
| Platelet | 148×10/μL (150–450×10/μL) |