Intermittent High-Frequency Percussive Ventilation Therapy in 3 Patients with Severe COVID-19 Pneumonia

05 February 2021: Articles

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment

Sergey P. Marchenko ^B* , Ecaterina Scarlatescu ^A , Paul Robert Vogt ^A , Alexey Naumov ^A , Sergey Bognenko ^A

DOI: 10.12659/AJCR.928421

Am J Case Rep 2021; 22:e928421

Table 1. Comorbidities, treatment, and laboratory findings.

Patient case number and DOD		Comorbidities	Treatment	Laboratory findings
Patient case number and DOD		Comorbidities	Treatment	WBC (109/l); (L/N ratio)	CRP (mg/l)	LDH (U/l)	D-dimers (µg/l)	Ferritin (µg/l)
1	DOD 16	Obesity, AH	LMWH, HCQ, AZT	8.5; (1.2)	66	300	500	319
	DOD 21		LMWH, HCQ, AZT	5.9; (1.3)	206	216	1099	502
	DOD 27		LMWH, HCQ, AZT	13.2;(1.2)	15	209	580	296
2	DOD 11	Obesity, AH, HF, AF, DM	LMWH, HCQ, AZT, spironolactone, torsemide, metoprolol, enalapril	6.1; (1.3)	76.4	233	1180	195
	DOD 18		LMWH, HCQ, AZT, DXM, metoprolol, spironolactone, enalapril	1.4;(1.6)	90.2	330	515	240
	DOD 25		LMWH, HCQ, meropenem, DXM, torsemide, spironolactone, enalapril	12.8; (1.3)	184.3	693	757	1092
	DOD 31		LMWH, metoprolol, torsemide, spironolactone, enalapril	6.0;(1.8)	34.7	402	681	371
3	DOD 12	Obesity, AH	LMWH, HCQ, AZT	5.3; (1.8)	61.3	226	190	433
	DOD 16		LMWH, HCQ, AZT	2.9; (1.9)	85.7	283	334	306
	DOD 18		LMWH, meropenem, DXM	15.2; (1.9)	94.3	199	402	320
	DOD 23		LMWH	4.2; (2.8)	2.5	181	311	180
WBC – white blood cell; N – neutrophils; L – lymphocytes; CRP – C-reactive protein; LDH – lactate dehydrogenase, DOD – day of disease onset; HCQ – hydroxychloroquine; AZT – azithromycin; LMWH – low molecular weight heparin; AH – arterial hypertension; HF – heart failure; DM – diabetes mellitus; AF – atrial fibrillation; DXM – dextromethorphan.