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16 February 2021: Articles

An Unusual Case of Neurosyphilis Manifesting as Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Unusual clinical course, Challenging differential diagnosis

Hannah L. Seay B* , Loura Khallouf B , Alyson Lieberman B , Sandeep S. Jubbal B

DOI: 10.12659/AJCR.929050

Am J Case Rep 2021; 22:e929050

Table 1. Laboratory values on admission.

Laboratory valuesDay 1Reference range
Hemoglobin (g/dL)13.113.2–17.1
Hematocrit (%)38.539–52
White blood cell count (10/uL)8.44.3–10.8
Sodium (mmol/L)124135–145
Potassium (mmol/L)4.43.5–5.3
Creatinine (mg/dL)0.810.60–1.30
Blood urea nitrogen (mg/dL)107–23
Rapid plasma reaginReactiveNon-reactive
Rapid plasma reagin titer1: 256
Fluorescent treponemal antibody absorptionReactiveNon-reactive
Chlamydia trachomatis, RNANot detectedNot detected
Neisseria gonorrhoeae RNANot detectedNot detected
Serum osmolality (mOsm/kg)264279–295
HIV-1 RNA (copies/mL)Not detected
HIV-1 RNA PCR (Log copies/mL)Not detected
Absolute CD4 (cells/uL)188370–1540
Cortisol AM (ug/dL)12.96.7–22.6
Specific gravity1.0301.005–1.030
Sodium (mmol/L)20
Creatinine (mg/dL)3222–328
Osmolality (mOsm/kg)14870–900
Glucose (mg/dL)6850–80
Protein (mg/dL)10715–45
Cryptococcal antigenNot detectedNot detected
HSV 1 PCRNot detectedNot detected
HSV 2 PCRNot detectedNot detected
CSF cultureNo growthNo growth
Venereal disease research laboratory testReactive 1: 4Non-reactive
CSF Gram stainNo organism seen
HSV 1 DNANot detectedNot detected
HSV 2 DNADetectedNot detected

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923