07 May 2021
: Case report 
A 41-Year-Old Woman with Excessive Fat of the Lower Body Since Puberty with Progression to Swollen Ankles and Feet Despite Caloric Restriction, Due to Lipedema and Protein-Calorie Malnutrition: A Case of Stage 3 Lipedema
Mistake in diagnosis, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology
Thomas F. Wright1ABDEF*, Karen L. Herbst23DEFDOI: 10.12659/AJCR.930306
Am J Case Rep 2021; 22:e930306
Table 1. Comparison of findings in lipedema, lymphedema, and lifestyle-induced obesity.
| Lipedema | Lymphedema | Lifestyle-induced obesity | |
|---|---|---|---|
| Sex | Women | Women and men | Women and men |
| Adiposity | Bilateral extremities | Unilateral or bilateral extremities | Whole body, proportionate |
| Symmetric | Asymmetric | Symmetric | |
| Edema | Non-pitting | Pitting | None |
| Minimal change with elevation; minimal change with compression | Reduced by elevation; reduced with compression (except in late stage) | No change with elevation or compression | |
| Tissue turgor | Soft | Firm | Soft |
| Pain | Tender to palpation | Usually nontender | None |
| Infection | Rare | Common | Rare |
| Shared with permission from author Herbst []. Originally published in Buck DW 2, Herbst KL. Lipedema: A relatively common disease with extremely common misconceptions. Plast Reconstr Surg Glob Open. 2016;4(9):e1043. | |||