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07 May 2021: Articles

A 41-Year-Old Woman with Excessive Fat of the Lower Body Since Puberty with Progression to Swollen Ankles and Feet Despite Caloric Restriction, Due to Lipedema and Protein-Calorie Malnutrition: A Case of Stage 3 Lipedema

Mistake in diagnosis, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology

Thomas F. Wright A* , Karen L. Herbst D

DOI: 10.12659/AJCR.930306

Am J Case Rep 2021; 22:e930306

Table 1. Comparison of findings in lipedema, lymphedema, and lifestyle-induced obesity.

LipedemaLymphedemaLifestyle-induced obesity
SexWomenWomen and menWomen and men
AdiposityBilateral extremitiesUnilateral or bilateral extremitiesWhole body, proportionate
SymmetricAsymmetricSymmetric
EdemaNon-pittingPittingNone
Minimal change with elevation; minimal change with compressionReduced by elevation; reduced with compression (except in late stage)No change with elevation or compression
Tissue turgorSoftFirmSoft
PainTender to palpationUsually nontenderNone
InfectionRareCommonRare
Shared with permission from author Herbst []. Originally published in Buck DW 2, Herbst KL. Lipedema: A relatively common disease with extremely common misconceptions. Plast Reconstr Surg Glob Open. 2016;4(9):e1043.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923