07 May 2021
: Case report
A 41-Year-Old Woman with Excessive Fat of the Lower Body Since Puberty with Progression to Swollen Ankles and Feet Despite Caloric Restriction, Due to Lipedema and Protein-Calorie Malnutrition: A Case of Stage 3 Lipedema
Mistake in diagnosis, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology
Thomas F. Wright1ABDEF*, Karen L. Herbst23DEFDOI: 10.12659/AJCR.930306
Am J Case Rep 2021; 22:e930306
Table 2. Diagnostic criteria for lipedema.
| Almost exclusive occurrence in women |
| Bilateral and symmetrical manifestation with minimal involvement of the feet |
| Minimal pitting edema |
| Negative Kaposi-Stemmer sign |
| Pain, tenderness on pressure |
| Easy bruising |
| Persistent enlargement after elevation of the extremities or weight loss |
| Arms are affected 80% of the time |
| Hypothermia of the skin |
| Swelling worsens with orthostasis in summer |
| Unaffected by caloric restriction |
| Telangiectasias |
| * Added by Herbst []. |






