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16 May 2021: Articles

Hydralazine-Induced Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Asymptomatic and Renal-Restricted Presentation

Challenging differential diagnosis, Unusual setting of medical care, Rare disease, Adverse events of drug therapy

Wan Tu A* , Barry Fayman A* , Stephen C. Ward B , Yusufal Mamoon A , Sabiha S. Bandagi C

DOI: 10.12659/AJCR.931263

Am J Case Rep 2021; 22:e931263

Table 2. Interventions at specific time points and outcomes.

Pre-admission MonthsAdmission
5 Years Ago4 Ago1 MonthAgoDay 0Day 3Day 4Day 7Day 9Day 11Post-admission 6 Weeks
Blood urea nitrogen (mg/dL)181427414130274257
Creatinine (mg/dL)0.911.052.053.993.623.012.812.672.36
GFR (mL/min/1.73 m2)816529141519202224
Protein (mg/mL)Neg300≥1000
White blood cells (/hpf)5–6>505–6
Red blood cells (/hpf)11–2011–204–6
ESR (mm/h)30
CRP (mg/L)
Ferritin (ng/mL)37120367
pANCA1: 12801: 12801: 1280
Hydrala-Serology resultedzine discon-tinuedKidney biopsy obtainedPO prednisone and mycophenolate startedMycopheno-late dose increased
cANCA – cytoplasmic antineutrophil cytoplasmic antibody; CRP – C-reactive protein; EST – erythrocyte sedimentation rate; GFR – glomerular filtration rate; pANCA – perinuclear antineutrophil cytoplasmic antibody; PO – by mouth.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923