Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 September 2022: Articles

Pyoderma Gangrenosum Mimicking Necrotizing Fasciitis on Magnetic Resonance Imaging: A Case Report and Literature Review

Unknown etiology, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Sungwoo Park B , Hyoshim Shin C , Dong Hyun Lee D , Eun-Ha Koh E , Jeong-Hee Lee D , Gyeong-Won Lee A*

DOI: 10.12659/AJCR.931734

Am J Case Rep 2022; 23:e931734

Table 1. Literature review of magnetic resonance imaging and histology of pyoderma gangrenosum.

AuthorAge/sexInitial diagnosisMRI findingHistologyTreatment and outcome
Lee []14 47/MDiabetic foot infectionCellulitis with myositis but no assertive abscess pocketNeutrophilic infiltrate in whole field with absence of squamous carcinoma or other malignancy
Yoshida []15 67/MPyoderma gangrenosum and sterile osteomyelitisLow intensity with T1-weighted phase and high intensity with T2-weighted phase in the sternum and the overlying fat and skin tissues, indicating severe inflammationEpidermal ulceration with prominent infiltration of neutrophils
Fonder []16 38/FPyoderma gangrenosumSuperficial T2 bright signal compatible with inflammation involving the subcutaneous tissue down to the level of the deep fasciaNecrosis, a mixed inflammatory infiltrate, and a small-vessel leukocytoclastic vasculitis
Jain []17 70/FCellulitisWound present medially in the distal calf with adjacent skin thickening along with circumferential subcutaneous edemaSevere acute cellulitis, abscess formation, and granulation tissue
Milind []18 49/MDisseminated tuberculosisSmall fluid collection adjacent to right ischial tuberosity suggesting an infective etiologyPerivascular lymphocytic infiltration with endothelial swelling and focal neutrophilic abscess
Husain []19 55/MUlcerative colitisA complex appearing, peripherally enhancing fluid collection within the subcutaneous tissues overlying the lateral aspect of the distal fibular metadiaphysis, associated with extensive subcutaneous edema extending along the lateral part of the distal leg and ankle in conjunction with mild cortical thickening and/or chronic periostitis of the distal tibia and fibulaDiffuse neutrophilic infiltrates throughout the dermis
Park [this case]67/FNecrotizing fasciitisHigh signal intensity in the left lower leg fascia and subcutaneous fat layerDiffuse acute inflammation in the dermis with an ulcer and neutrophilic infiltration is apparent in the histopathological examination of the skin lesion
MRI – magnetic resonance imaging.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923